JAK1 antibody | rKL01/3C7
Mouse anti Human JAK1
- Product Type
- Monoclonal Antibody
- Clone
- rKL01/3C7
- Isotype
- IgG2a
- Specificity
- JAK1
Antibody Quality and Performance Guarantee
MCA6441GA
| Mouse anti Human JAK1 antibody, clone rKL01/3C7 recognizes the Tyrosine-protein kinase JAK1, also known as Janus kinase 1. Janus kinases form a family of intracellular, non-receptor tyrosine kinases that transduce cytokine-mediated signals via the JAK-STAT pathway. In cancer, JAK1 appears to act either as an oncogene or as a tumor-suppressor depending on the conditions or the cell content. |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Purified recombinant IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Source
- CHO-S
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Immunogen
- E. coli-derived recombinant protein, amino acids 32-286 of human JAK1
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting |  |
1/1,000 |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- UniProt
- P23458
- Entrez Gene
- JAK1
- GO Terms
- GO:0016020 membrane
- GO:0005829 cytosol
- GO:0004715 non-membrane spanning protein tyrosine kinase activity
- GO:0005131 growth hormone receptor binding
- GO:0005524 ATP binding
- GO:0005634 nucleus
- GO:0005856 cytoskeleton
- GO:0012505 endomembrane system
- GO:0046677 response to antibiotic
- View More GO Terms
- GO:0060333 interferon-gamma-mediated signaling pathway
- GO:0060334 regulation of interferon-gamma-mediated signaling pathway
- GO:0060337 type I interferon-mediated signaling pathway
- GO:0060338 regulation of type I interferon-mediated signaling pathway
MCA6441GA
64612316
If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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