IP-10 antibody | 4D5

Mouse anti Human IP-10

Product Type
Monoclonal Antibody
Clone
4D5
Isotype
IgG2a
Specificity
IP-10

Product Code Applications Pack Size List Price Your Price Qty
MCA1693
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
E WB 0.5 mg loader
List Price Your Price
loader
Search for Batch Specific Datasheets

Mouse anti Human IP-10 antibody, clone 4D5 recognizes human C-X-C motif chemokine 10, also known as IP-10, Small-inducible cytokine B10 or CXCL10. IP-10 is a 98 amino acid ~10kDa CxC chemokine induced by interferon γ.

Target Species
Human
Product Form
Purified IgG - liquid
Preparation
Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% sodium azide (NaN3)
Carrier Free
Yes
Immunogen
Recombinant human IP-10.
Approx. Protein Concentrations
IgG concentration 1.0 mg/ml
Fusion Partners
Spleen cells from immunised Balb/c mice were fused with cells of the mouse P3X63-AgP-653 myeloma cell line
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA 1ug/ml 2ug/ml
Immunohistology - Frozen
Immunohistology - Paraffin
Western Blotting 1/1000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

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References for IP-10 antibody

  1. Wetzel, M.A. et al. (2000) Mu-opioid induction of monocyte chemoattractant protein-1, RANTES, and IFN-gamma-inducible protein-10 expression in human peripheral blood mononuclear cells.
    J Immunol. 165: 6519-24.
  2. De Paepe, B. et al. (2012) Upregulation of chemokines and their receptors in Duchenne muscular dystrophy: potential for attenuation of myofiber necrosis.
    Muscle Nerve. 46 (6): 917-25.

Synonyms
CXCL10
RRID
AB_2087882
UniProt
P02778
Entrez Gene
CXCL10
GO Terms
GO:0005615 extracellular space
GO:0006935 chemotaxis
GO:0006954 inflammatory response
GO:0007166 cell surface receptor linked signaling pathway
GO:0007267 cell-cell signaling
GO:0007517 muscle organ development
GO:0008009 chemokine activity
GO:0008015 blood circulation
GO:0008284 positive regulation of cell proliferation
GO:0008603 cAMP-dependent protein kinase regulator activity
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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