IP-10 antibody | 4D5

Mouse anti Human IP-10
- Product Type
- Monoclonal Antibody
- Clone
- 4D5
- Isotype
- IgG2a
- Specificity
- IP-10
Mouse anti Human IP-10 antibody, clone 4D5 recognizes human C-X-C motif chemokine 10, also known as IP-10, Small-inducible cytokine B10 or CXCL10. IP-10 is a 98 amino acid ~10kDa CxC chemokine induced by interferon γ. |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% sodium azide (NaN3)
- Carrier Free
- Yes
- Immunogen
- Recombinant human IP-10.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Fusion Partners
- Spleen cells from immunised Balb/c mice were fused with cells of the mouse P3X63-AgP-653 myeloma cell line
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
ELISA | ![]() |
1ug/ml | 2ug/ml |
Immunohistology - Frozen | |||
Immunohistology - Paraffin | |||
Western Blotting | ![]() |
1/1000 |
References for IP-10 antibody
-
Wetzel, M.A. et al. (2000) Mu-opioid induction of monocyte chemoattractant protein-1, RANTES, and IFN-gamma-inducible protein-10 expression in human peripheral blood mononuclear cells.
J Immunol. 165: 6519-24. -
De Paepe, B. et al. (2012) Upregulation of chemokines and their receptors in Duchenne muscular dystrophy: potential for attenuation of myofiber necrosis.
Muscle Nerve. 46 (6): 917-25.
- Synonyms
- CXCL10
- RRID
- AB_2087882
- UniProt
- P02778
- Entrez Gene
- CXCL10
- GO Terms
- GO:0005615 extracellular space
- GO:0006935 chemotaxis
- GO:0006954 inflammatory response
- GO:0007166 cell surface receptor linked signaling pathway
- GO:0007267 cell-cell signaling
- GO:0007517 muscle organ development
- GO:0008009 chemokine activity
- GO:0008015 blood circulation
- GO:0008284 positive regulation of cell proliferation
- View More GO Terms
- GO:0008603 cAMP-dependent protein kinase regulator activity
MCA1693



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