Integrin Alpha V Beta 5 antibody | P1F6
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Mouse anti Human Integrin Alpha V Beta 5
- Product Type
- Monoclonal Antibody
- Clone
- P1F6
- Isotype
- IgG1
- Specificity
- Integrin Alpha V Beta 5
Antibody Quality and Performance Guarantee
| Mouse anti Human integrin alpha V beta 5 antibody, clone P1F6 recognizes the integrin alpha V beta 5 holomolecule. ITGaVb5 acts as a receptor for fibronectin and has also been co-opted as a cellular receptor for adenovirus type C (Lyle and McCormick 2010). |
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Chicken - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein A from ascites
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.1% Sodium Azide (NaN3)
- Immunogen
- Human UCLA P3 cells (lung carcinoma).
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |  |
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| Flow Cytometry | |
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| Immunofluorescence | |
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| Immunohistology - Frozen | |
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| Immunoprecipitation | |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.
- Immunohistology
- For use on human carcinomas, normal epithelium and keratinocytes using acetone or paraformaldehyde fixed tissue sections.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Mouse IgG1 Negative Control | MCA928 | F | 100 Tests |
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| List Price | Your Price | ||||||
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| Description | Mouse IgG1 Negative Control | ||||||
References for Integrin Alpha V Beta 5 antibody
-
Aplin, J. D. et al. (1996) Integrins beta 5, beta 3 and alpha v are apically distributed in endometrial epithelium
Mol Hum Reprod 2: 527 - 534 -
Weinacker, A. et al. (1994) Role of the integrin alpha v beta 6 in cell attachment to fibronectin. Heterologous expression of intact and secreted forms of the receptor
J Biol Chem 269: 6940 - 6948 -
Wayner, E. A. et al. (1991) Integrins alpha v beta 3 and alpha v beta 5 contribute to cell attachment to vitronectin but differentially distribute on the cell surface
J Cell Biol 113: 919 - 929
- Synonyms
- CD51
- RRID
- AB_620176
- UniProt
- P18084
- P06756
- Entrez Gene
- ITGAV
- ITGB5
- GO Terms
- GO:0005515 protein binding
- GO:0007596 blood coagulation
- GO:0004872 receptor activity
- GO:0008305 integrin complex
- GO:0007160 cell-matrix adhesion
- GO:0007229 integrin-mediated signaling pathway
- GO:0007411 axon guidance
- GO:0010745 negative regulation of macrophage derived foam cell differentiation
- GO:0010888 negative regulation of lipid storage
- View More GO Terms
- GO:0032369 negative regulation of lipid transport
- GO:0044419 interspecies interaction between organisms
- GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process
- GO:0050748 negative regulation of lipoprotein metabolic process
- GO:0050900 leukocyte migration
- GO:0006936 muscle contraction
- GO:0007275 multicellular organismal development
5355-2657
145506
160380
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