IL-6 antibody | C01-1E8
Mouse anti Human Interleukin-6
- Product Type
- Monoclonal Antibody
- Clone
- C01-1E8
- Isotype
- IgG2a
- Specificity
- IL-6
Mouse anti Human interleukin-6 antibody, clone C01-1E8 recognizes human interleukin 6, also known as B-cell stimulatory factor 2, CTL differentiation factor, Hybridoma growth factor or Interferon beta-2. Interleukin-6 is a 183 amino acid ~24 kDa cytokine with a wide range of biological activities. Interleukin-6 is a potent inducer of the acute phase response, acts as a lymphoid cell growth factor acting on B cells, T cells and hybridoma cells. Variations in the interleukin-6 gene modulates susceptibility to onset of juvenile systemic rheumatoid arthritis (RASJ) an inflammatory disorder with early onset and featuring lymphadenopathy, hepatosplenomegaly, serositis, myalgia and arthritis (Fishman et al. 1998). The purified Mouse anti Human interleukin-6 antibody, clone C01-1E8 (MCA6333GA) can be used as a capture antibody in a sandwich ELISA with the biotinylated Mouse anti Human interleukin-6 antibody, clone J06-1E12 (MCA6334B) as the detection antibody. |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Carrier Free
- Yes
- Immunogen
- E. coli derived recombinant human full length interleukin-6 (Val30-Met212).
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Fusion Partners
- Cell fusion between immunized BALB/c mouse spleen cells and mouse myeloma SP2/0.
- ELISA Matched Pair(s)
- ELISA Matched Pair-Detection Antibody: MCA6334B
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
ELISA | 1.0 ug/ml |
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
---|---|---|---|---|---|---|---|
Mouse anti Human Interleukin-6:Biotin | MCA6334B | E | 0.1 mg | Log in | |||
List Price | Your Price | ||||||
Log in | |||||||
Description | Mouse anti Human Interleukin-6:Biotin |
- UniProt
- P05231
- Entrez Gene
- IL6
- GO Terms
- GO:0001781 neutrophil apoptosis
- GO:0002384 hepatic immune response
- GO:0002446 neutrophil mediated immunity
- GO:0002548 monocyte chemotaxis
- GO:0002675 positive regulation of acute inflammatory response
- GO:0002690 positive regulation of leukocyte chemotaxis
- GO:0006953 acute-phase response
- GO:0005125 cytokine activity
- GO:0005138 interleukin-6 receptor binding
- View More GO Terms
- GO:0005615 extracellular space
- GO:0005896 interleukin-6 receptor complex
- GO:0006959 humoral immune response
- GO:0008083 growth factor activity
- GO:0050830 defense response to Gram-positive bacterium
- GO:0050829 defense response to Gram-negative bacterium
- GO:0008285 negative regulation of cell proliferation
- GO:0010574 regulation of vascular endothelial growth factor production
- GO:0010888 negative regulation of lipid storage
- GO:0045727 positive regulation of translation
- GO:0030168 platelet activation
- GO:0031018 endocrine pancreas development
- GO:0031175 neuron projection development
- GO:0032494 response to peptidoglycan
- GO:0032722 positive regulation of chemokine production
- GO:0032755 positive regulation of interleukin-6 production
- GO:0032966 negative regulation of collagen biosynthetic process
- GO:0033138 positive regulation of peptidyl-serine phosphorylation
- GO:0042102 positive regulation of T cell proliferation
- GO:0042517 positive regulation of tyrosine phosphorylation of Stat3 protein
- GO:0043066 negative regulation of apoptosis
- GO:0043193 positive regulation of gene-specific transcription
- GO:0043410 positive regulation of MAPKKK cascade
- GO:0045079 negative regulation of chemokine biosynthetic process
- GO:0045599 negative regulation of fat cell differentiation
- GO:0045669 positive regulation of osteoblast differentiation
- GO:0045765 regulation of angiogenesis
- GO:0045768 positive regulation of anti-apoptosis
- GO:0045944 positive regulation of transcription from RNA polymerase II promoter
- GO:0048661 positive regulation of smooth muscle cell proliferation
- GO:0050871 positive regulation of B cell activation
- GO:0051024 positive regulation of immunoglobulin secretion
- GO:0051091 positive regulation of transcription factor activity
- GO:0051384 response to glucocorticoid stimulus
- GO:0051607 defense response to virus
- GO:0070091 glucagon secretion
- GO:0070102 interleukin-6-mediated signaling pathway
MCA6333GA
100005430If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
View all Anti-Human ProductsAlways be the first to know.
When we launch new products and resources to help you achieve more in the lab.
Yes, sign me up