hCG antibody | INN-hCG-2
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Mouse anti hCG (Beta 1 Epitope)
- Product Type
- Monoclonal Antibody
- Clone
- INN-hCG-2
- Isotype
- IgG1
- Specificity
- hCG
- Region
- (BETA 1 EPITOPE)
Antibody Quality and Performance Guarantee
| Mouse anti hCG antibody, clone INN-hCG-2 recognizes the beta 1 epitope on human chorionic gonadotrophin (hCG). Chorionic gonadotrophin is a member of the glycoprotein hormone family that is synthesized by the placenta throughout pregnancy. The glycoprotein hormone family has 4 members, the other three being luteinising hormone (LH), follicle stimulating hormone (FSH) and thyroid stimulating hormone (TSH). All consist of two subunits, alpha and beta. The alpha subunit is highly homologous between family members. Mouse anti hCG antibody, clone INN-hCG-2 is reactive with hCG, hCGbeta, hCGbetacf (fragment), hCGn (nicked), hCGbetan, and CTP-hCG. No cross reaction is observed with hLH, hLHbeta, hFSH, hTSH, or the glycoprotein hormone alpha chains. |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.09% Sodium Azide - Carrier Free
- Yes
- Immunogen
- hCG.
- Approx. Protein Concentrations
- Ig concentration 1.0 mg/ml
- Fusion Partners
- Spleen cells from an immunised BALB/c mouse were fused with the mouse P3-NS1/1 - Ag 4.1 myeloma cell line.
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Store at +4oC. DO NOT FREEZE.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |  |
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| Flow Cytometry | |||
| Immunoassay | |
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| Immunohistology - Paraffin | |
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| Radioimmunoassays | |
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
References for hCG antibody
-
Kofler, R. et al. (1982) Monoclonal antibodies against human chorionic gonadotropin (hCG): I. production, specificity, and intramolecular binding sites.
Am J Reprod Immunol. 2 (4): 212-6. -
Berger, P. et al. (1993) Variants of human chorionic gonadotropin from pregnant women and tumor patients recognized by monoclonal antibodies.
J Clin Endocrinol Metab. 77 (2): 347-51. -
Zimmermann, G. et al. (2009) Zimmermann G, Ackermann W, Alexander H. Epithelial human chorionic
Epithelial human chorionic gonadotropin is expressed and produced in human secretory endometrium during the
normal menstrual cycle. Biol Reprod. 2009 May;80(5):1053-65. Epub 2009 Jan 21.
PubMed PMID: 19164178.
Biol Reprod. 80:1053-65. -
Zimmermann, G. et al. (2003) Expression of beta hCG and alpha CG mRNA and hCG hormone in human decidual tissue in patients during tubal pregnancy.
Mol Hum Reprod. 9: 81-9. -
Charrel-Dennis, M. et al. (2005) The human chorionic gonadotropin-beta arginine68 to glutamic acid substitution fixes the conformation of the C-terminal peptide.
Mol Endocrinol. 19: 1803-11. -
Schwalenberg, T. et al. (2012) Enhanced urothelial expression of human chorionic gonadotropin beta (hCGβ) in bladder pain syndrome/interstitial cystitis (BPS/IC).
World J Urol. 30 (3): 411-7.
- RRID
- AB_2260450
- UniProt
- P01233
- Entrez Gene
- CGB
MCA19
154374
162876
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