hCG antibody | INN-hCG-2
|Mouse anti hCG antibody, clone INN-hCG-2 recognizes the beta 1 epitope on human chorionic gonadotrophin (hCG).
Chorionic gonadotrophin is a member of the glycoprotein hormone family that is synthesized by the placenta throughout pregnancy. The glycoprotein hormone family has 4 members, the other three being luteinising hormone (LH), follicle stimulating hormone (FSH) and thyroid stimulating hormone (TSH). All consist of two subunits, alpha and beta. The alpha subunit is highly homologous between family members.
Mouse anti hCG antibody, clone INN-hCG-2 is reactive with hCG, hCGbeta, hCGbetacf (fragment), hCGn (nicked), hCGbetan, and CTP-hCG. No cross reaction is observed with hLH, hLHbeta, hFSH, hTSH, or the glycoprotein hormone alpha chains.
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein A
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.09% Sodium Azide
- Carrier Free
- Approx. Protein Concentrations
- Ig concentration 1.0 mg/ml
- Fusion Partners
- Spleen cells from an immunised BALB/c mouse were fused with the mouse P3-NS1/1 - Ag 4.1 myeloma cell line.
- For research purposes only
- 12 months from date of despatch
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
|Application Name||Verified||Min Dilution||Max Dilution|
|Immunohistology - Paraffin|
References for hCG antibody
Kofler, R. et al. (1982) Monoclonal antibodies against human chorionic gonadotropin (hCG): I. production, specificity, and intramolecular binding sites.
Am J Reprod Immunol. 2 (4): 212-6.
Berger, P. et al. (1993) Variants of human chorionic gonadotropin from pregnant women and tumor patients recognized by monoclonal antibodies.
J Clin Endocrinol Metab. 77 (2): 347-51.
Zimmermann, G. et al. (2009) Zimmermann G, Ackermann W, Alexander H. Epithelial human chorionic
Epithelial human chorionic gonadotropin is expressed and produced in human secretory endometrium during the
normal menstrual cycle. Biol Reprod. 2009 May;80(5):1053-65. Epub 2009 Jan 21.
PubMed PMID: 19164178.
Biol Reprod. 80:1053-65.
Zimmermann, G. et al. (2003) Expression of beta hCG and alpha CG mRNA and hCG hormone in human decidual tissue in patients during tubal pregnancy.
Mol Hum Reprod. 9: 81-9.
Charrel-Dennis, M. et al. (2005) The human chorionic gonadotropin-beta arginine68 to glutamic acid substitution fixes the conformation of the C-terminal peptide.
Mol Endocrinol. 19: 1803-11.
Schwalenberg, T. et al. (2012) Enhanced urothelial expression of human chorionic gonadotropin beta (hCGβ) in bladder pain syndrome/interstitial cystitis (BPS/IC).
World J Urol. 30 (3): 411-7.
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