Galectin-8 antibody | 106.1
|Mouse anti Human galectin-8 antibody, clone 106.1, recognizes galectin-8 also known as Po66 carboxyhydrate binding protein. Galectin-8 expressed in many tissues including kidney, liver, cardiac muscle, lung, breast, colon, retina, pancreas, placenta, spleen, testis, uterus, vascular esophagus and brain (Hadari et al. 1995).
Galectin-8 is a member of the galactin family of proteins which cross-link cell surface glycol proteins in the extracellular space upon secretion and plays a role in many biological processes including cell growth and migration. Galectin-8 can either positively or negatively regulate cell adhesion, depending on the extracellular context. When at high concentrations galectin-8 has also been shown to trigger antigen independent proliferation of CD4+ T cells. While at low levels galectin-8 can act in a co-stimulatory signaling capacity that synergizes antigen specific CD4+ T cell responses (Metz et al. 2016).
- Target Species
- Species Cross-Reactivity
Target Species Cross Reactivity Rat
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein G
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Recombinant rat Galectin-8
- Approx. Protein Concentrations
- IgG concentration 0.1 mg/ml
- For research purposes only
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
|Application Name||Verified||Min Dilution||Max Dilution|
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