Galectin-8 antibody | 106.1
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Mouse anti Human GALECTIN-8
- Product Type
- Monoclonal Antibody
- Clone
- 106.1
- Isotype
- IgG2a
- Specificity
- Galectin-8
Antibody Quality and Performance Guarantee
| Mouse anti Human galectin-8 antibody, clone 106.1, recognizes galectin-8 also known as Po66 carboxyhydrate binding protein. Galectin-8 expressed in many tissues including kidney, liver, cardiac muscle, lung, breast, colon, retina, pancreas, placenta, spleen, testis, uterus, vascular esophagus and brain (Hadari et al. 1995). Galectin-8 is a member of the galactin family of proteins which cross-link cell surface glycol proteins in the extracellular space upon secretion and plays a role in many biological processes including cell growth and migration. Galectin-8 can either positively or negatively regulate cell adhesion, depending on the extracellular context. When at high concentrations galectin-8 has also been shown to trigger antigen independent proliferation of CD4+ T cells. While at low levels galectin-8 can act in a co-stimulatory signaling capacity that synergizes antigen specific CD4+ T cell responses (Metz et al. 2016). |
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Rat - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Immunogen
- Recombinant rat Galectin-8
- Approx. Protein Concentrations
- IgG concentration 0.1 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |  |
1/50 | |
| Flow Cytometry | |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Mouse IgG2a Negative Control | MCA929 | F | 100 Tests |
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| List Price | Your Price | ||||||
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| Description | Mouse IgG2a Negative Control | ||||||
MCA6153GA
157926
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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