Galectin-8 antibody | 106.1

Mouse anti Human GALECTIN-8

Product Type
Monoclonal Antibody
Clone
106.1
Isotype
IgG2a
Specificity
Galectin-8

Product Code Applications Pack Size List Price Your Price Qty
MCA6153GA
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
E F 0.1 mg loader
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loader
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Mouse anti Human galectin-8 antibody, clone 106.1, recognizes galectin-8 also known as Po66 carboxyhydrate binding protein. Galectin-8 expressed in many tissues including kidney, liver, cardiac muscle, lung, breast, colon, retina, pancreas, placenta, spleen, testis, uterus, vascular esophagus and brain (Hadari et al. 1995).

Galectin-8 is a member of the galactin family of proteins which cross-link cell surface glycol proteins in the extracellular space upon secretion and plays a role in many biological processes including cell growth and migration. Galectin-8 can either positively or negatively regulate cell adhesion, depending on the extracellular context. When at high concentrations galectin-8 has also been shown to trigger antigen independent proliferation of CD4+ T cells. While at low levels galectin-8 can act in a co-stimulatory signaling capacity that synergizes antigen specific CD4+ T cell responses (Metz et al. 2016).

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Rat
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Purified IgG prepared by affinity chromatography on Protein G
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
Immunogen
Recombinant rat Galectin-8
Approx. Protein Concentrations
IgG concentration 0.1 mg/ml
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA 1/50
Flow Cytometry
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

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Description Goat anti Mouse IgG (H/L):FITC (Multi Species Adsorbed)
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Description Goat anti Mouse IgG (Fc):FITC
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Description Rabbit F(ab')2 anti Mouse IgG:HRP (Human Adsorbed)
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Description Goat anti Mouse IgG:RPE (Rat Adsorbed)
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Description Goat anti Mouse IgG/A/M:Alk. Phos.
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Description Goat anti Mouse IgG/A/M:HRP (Human Adsorbed)
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Description Rabbit F(ab')2 anti Mouse IgG:Dylight®800
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Description Rabbit F(ab')2 anti Mouse IgG:FITC

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Description Mouse IgG2a Negative Control

UniProt
O00214
Entrez Gene
LGALS8
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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