FES antibody | AB04-4F6

Filter by Application:
WB ResetMouse anti Human FES
- Product Type
- Monoclonal Antibody
- Clone
- AB04-4F6
- Isotype
- IgG1
- Specificity
- FES
Mouse anti human FES antibody, clone AB04-4F6
recognizes tyrosine-protein kinase FES/FPS, otherwise known as feline sarcoma/fujinami avian sarcoma oncogene homolog, proto-oncogene c-FES, proto-oncogene c-FPS or p93c-FES. FES is one of two members of a unique family of cytoplasmic protein tyrosine kinases, alongside tyrosine-protein kinase FER. This family of kinases contains a central src homology-2 (SH2) domain and a COOH-terminal tyrosine kinase catalytic domain and are distinct from other members of cytoplasmic protein tyrosine kinase subfamilies by the presence of NH2-terminal FER/CIP4 homology and coiled-coil domains (Sangrar et al. 2005). Studies initially suggested that mutations in FES contribute to the development of some cancers (Ley et al. 2003). However, more recent research has shown that FES may act a tumor suppressor in colorectal cancer (Delfino et al. 2006). |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Immunogen
- E. coli-derived recombinant protein, aa 1-459 of human FES
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Western Blotting | ![]() |
1/1,000 |
- Western Blotting
- Mouse anti Human FES antibody detects a band of 94 kDa in THP-1 cell lysate
- UniProt
- P07332
- Entrez Gene
- FES
- GO Terms
- GO:0005829 cytosol
- GO:0004715 non-membrane spanning protein tyrosine kinase activity
- GO:0005524 ATP binding
- GO:0007411 axon guidance
- GO:0008283 cell proliferation
- GO:0018108 peptidyl-tyrosine phosphorylation
MCA6412GA

If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
View all Anti-Human ProductsAlways be the first to know.
When we launch new products and resources to help you achieve more in the lab.
Yes, sign me up