Elastase antibody | ELA10-101.5 (39A)

Product Details
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.09% Sodium Azide (NaN3) - Immunogen
- Elastase from human neutrophils.
- Approx. Protein Concentrations
- 0.5 mg/ml
Storage Information
- Storage
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. - Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P08246
- Entrez Gene
- ELANE
- GO Terms
- GO:0005576 extracellular region
- GO:0030141 stored secretory granule
- GO:0006508 proteolysis
- GO:0006874 cellular calcium ion homeostasis
- GO:0008201 heparin binding
- GO:0009411 response to UV
- GO:0009986 cell surface
- GO:0019955 cytokine binding
- GO:0030163 protein catabolic process
- GO:0043406 positive regulation of MAP kinase activity
- GO:0045079 negative regulation of chemokine biosynthetic process
- GO:0045415 negative regulation of interleukin-8 biosynthetic process
- GO:0045416 positive regulation of interleukin-8 biosynthetic process
- GO:0048661 positive regulation of smooth muscle cell proliferation
- GO:0050728 negative regulation of inflammatory response
- GO:0050922 negative regulation of chemotaxis
- GO:0051635 bacterial cell surface binding
- Regulatory
- For research purposes only
Applications of Elastase antibody
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
ELISA | |||
Flow Cytometry | |||
Functional Assays |
Secondary Antibodies Available
Negative Isotype Controls Available
Description | Product Code | Applications | Pack Size | List Price | Quantity |
---|---|---|---|---|---|
Mouse IgG1 Negative Control | MCA928 | F | 100 Tests |
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Product Specific References
References for Elastase antibody
-
Durant, S. et al. (2004) Apoptosis-induced proteinase 3 membrane expression is independent from degranulation.
J Leukoc Biol. 75 (1): 87-98. -
Vong, L. et al. (2007) Annexin 1 cleavage in activated neutrophils: a pivotal role for proteinase 3.
J Biol Chem. 282 (41): 29998-30004. -
Davies, P.L. et al. (2008) Monoclonal anti-neutrophil elastase antibody characterisation: ability to block function, detect free versus serpin-complexed enzyme and stain intracellular granules.
J Immunol Methods. 336 (2): 175-82. -
Muthana, M. et al. (2015) C5orf30 is a negative regulator of tissue damage in rheumatoid arthritis.
Proc Natl Acad Sci U S A. 112 (37): 11618-23. -
Buján, J. et al. (2003) Expression of elastic components in healthy and varicose veins.
World J Surg. 27 (8): 901-5. -
Korkmaz, B. et al. (2005) Inhibition of neutrophil elastase by alpha1-protease inhibitor at the surface of human polymorphonuclear neutrophils.
J Immunol. 175 (5): 3329-38.
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