D-Dimer antibody | DD5
|Mouse anti Human D-dimer antibody, clone DD5 recognises human D-dimer and shows low cross-reactivity with fibrinogen (D-monomer).
D-dimers are the principle degradation products of cross-linked fibrin, released into the bloodstream following the digestion of fibrin clots (thrombus) by the enzyme plasmin, and thus measurement of the level of D-dimer in plasma, can be used as an indication of thrombotic disorders. Conditions in which levels of D-dimer are elevated include deep vein thrombosis (DVT), venous thromboembolism (VTE), cardiovascular disease and disseminated intravascular coagulation (DIC), a possible acute condition arising from surgical operations, septic shock and liver disease.
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein A from ascites
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- <0.1% Sodium Azide (NaN3)
- Homogenised fibrin clot.
- Approx. Protein Concentrations
- IgG concentration 1.0mg/ml
- Fusion Partners
- Spleen cells from immunised Balb/c mice were fused with cells of the Sp2/0 myeloma cell line.
- For research purposes only
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
|Application Name||Verified||Min Dilution||Max Dilution|
|Western Blotting 1|
- 1This antibody recognises human D-dimer under non-reducing conditions.
References for D-Dimer antibody
- Entrez Gene
- GO Terms
- GO:0002576 platelet degranulation
- GO:0030674 protein binding, bridging
- GO:0005102 receptor binding
- GO:0007165 signal transduction
- GO:0005577 fibrinogen complex
- GO:0009897 external side of plasma membrane
- GO:0030168 platelet activation
- GO:0031093 platelet alpha granule lumen
- GO:0043499 eukaryotic cell surface binding
- View More GO Terms
- GO:0051258 protein polymerization
- GO:0051592 response to calcium ion
- GO:0051087 chaperone binding
- GO:0005625 soluble fraction
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