Mouse anti Human CD98 antibody, clone 44D7 reacts with the heavy chain of the CD98 molecule. The same epitope as recognized by clone 4F2. This antibody binds to all cell lines in culture and to activated T-cells.
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatent.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- Carrier Free
- HOON pre-B leukaemia cell line.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Fusion Partners
- Spleen cells from immunized BALB/c mice were fused with cells of the SP2/0-Ag14 mouse myeloma cell line.
- Store at +4oC or at -20oC if preferred.
Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 18 months from date of despatch.
- Entrez Gene
- GO Terms
integral to membrane
calcium:sodium antiporter activity
carbohydrate metabolic process
neutral amino acid transmembrane transporter activity
apical plasma membrane
cellular nitrogen compound metabolic process
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of CD98 antibody
|Immunohistology - Frozen
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
- Flow Cytometry
- Use 10ul of the suggested working dilution to label 106 cells in 100ul.
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Secondary Antibodies Available
Negative Isotype Controls Available
Application Based External Images
Product Specific References
References for CD98 antibody
Letarte, M. et al. (1986) Correlations between the 44D7 antigenic complex and the plasma membrane Na+-Ca2+ exchanger.
Biochem Cell Biol. 64 (11): 1160-9.
Jaramillo, R. et al. (2013) Relation between objective measures of atopy and myocardial infarction in the United States.
J Allergy Clin Immunol. 131 (2): 405-11.e1-11.
Månsson, A. et al. (2010) Leukocyte phenotype changes induced by specific immunotherapy in patients with birch allergy.
J Investig Allergol Clin Immunol. 20 (6): 476-83.
Millrud, C.R. et al. (2012) The activation pattern of blood leukocytes in head and neck squamous cell carcinoma is correlated to survival.
PLoS One. 7 (12): e51120.
Garrigues, H.J. et al. (2014) KSHV attachment and entry are dependent on αVβ3 integrin localized to specific cell surface microdomains and do not correlate with the presence of heparan sulfate.
Virology. 464-465: 118-133.