CD96 antibody | NK92.39
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F ResetMouse anti Human CD96
- Product Type
- Monoclonal Antibody
- Clone
- NK92.39
- Isotype
- IgG1
- Specificity
- CD96
Antibody Quality and Performance Guarantee
| Mouse anti Human CD96 antibody, clone NK92.39 recognizes human CD96, otherwise known as Tactile (T cell-activated increased late expression), a type I transmembrane glycoprotein expressed at low levels on peripheral resting T and NK cells, which increases following activation. CD96 stimulates the cytotoxicity of activated NK cells, and promotes the adhesion of NK cells to target cells expressing CD155/poliovirus receptor (PVR) and the transfer of target cell PVR to the NK cells. CD96 can be used in the immunophenotyping of T-cell acute lymphoblastic leukaemias (ALL) and acute myeloid leukaemias (AML), and may play a role in the recognition of CD155-expressing tumours by NK cells. Mouse anti Human CD96 antibody, clone NK92.39 blocks the binding of soluble CD155 to NK92 cells (Fuchs et al. 2004). |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- MCA4643GA: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- MCA4643: Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Carrier Free
- Yes
- Immunogen
- Natural killer 92 (NK92) cell line.
- Approx. Protein Concentrations
- IgG concentration 1.0mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Flow Cytometry |  |
1/10 | 1/200 |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Flow Cytometry
- Use 10ul of the suggested working dilution to label 1x106 cells in 100ul.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Mouse IgG1 Negative Control | MCA928 | F | 100 Tests |
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| List Price | Your Price | ||||||
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| Description | Mouse IgG1 Negative Control | ||||||
References for CD96 antibody
-
Fuchs, A. et al. (2004) Cutting edge: CD96 (tactile) promotes NK cell-target cell adhesion by interacting with the poliovirus receptor (CD155).
J Immunol. 172 (7): 3994-8.
- Synonyms
- Tactile
- RRID
- AB_1628787
- UniProt
- P40200
- Entrez Gene
- CD96
- GO Terms
- GO:0007155 cell adhesion
- GO:0005887 integral to plasma membrane
- GO:0006955 immune response
- GO:0050776 regulation of immune response
MCA4643GA
150984
MCA4643
150983
158802
If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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