CD56 antibody | rAB03-1H8
Mouse anti Human CD56
- Product Type
- Monoclonal Antibody
- Clone
- rAB03-1H8
- Isotype
- IgG1
- Specificity
- CD56
Filter by Application:
F Reset| Mouse anti Human CD56 antibody, clone rAB03-1H8, is a recombinant monoclonal antibody that recognizes CD56, also known as human neural cell adhesion molecule (NCAM). CD56 is a cell surface glycoprotein of the immunoglobulin superfamily. In the human hematopoietic system, CD56 is expressed on natural killer (NK) cells, alpha beta T cells, gamma delta T cells, dendritic cells and monocytes. As the name suggests, it is also expressed by cells of neuronal lineage. Three main isoforms of CD56 exist that differ in the intracellular domain. In NK cells, CD56 has been shown to act as a pathogen recognition receptor, promote cytotoxicity and stimulate exocytosis. In neuronal tissues, CD56 mediates homophilic and heterophilic adhesion, and is implicated in neural development, cell migration and synaptic plasticity. CD56 is considered a classical surface marker of NK cells, which are usually divided into two subsets, CD56dim and CD56bright. NK cells in peripheral blood are predominantly CD56dim, whilst CD56bright NK cells are more prevalent in tissues. Expression of CD56 by NK cells can be used as an activation marker. Aberrant CD56 expression is associated with a range of tumors and malignancies, including tumors of the lung, neural derived malignancies, and natural killer cell lymphomas. |
- Target Species
- Human
- Product Form
- Purified recombinant IgG containing a SpyTag at the C-terminus of the antibody heavy chain – liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
- Source
- CHO cells
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Carrier Free
- Yes
- Immunogen
- Recombinant CD56 Leu20-Ala708 expressed by mammalian cells
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
- Acknowledgements
- This product and/or its use is covered by claims of U.S. patents, and/or pending U.S. and non-U.S. patent applications owned by or under license to Bio-Rad Laboratories, Inc. See bio-rad.com/en-us/trademarks for details.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Flow Cytometry |
- Flow Cytometry
- Use 5μl of the suggested working dilution to label 0.5x106 cells in 100μl. Best practices suggest a 5 min centrifugation at 6,000g prior to sample application.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Mouse IgG1 Negative Control | MCA928 | F | 100 Tests |
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| List Price | Your Price | ||||||
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| Description | Mouse IgG1 Negative Control | ||||||
TZA062GA
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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