CD1c antibody | L161
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F ResetMouse anti Human CD1c
- Product Type
- Monoclonal Antibody
- Clone
- L161
- Isotype
- IgG1
- Specificity
- CD1c
Antibody Quality and 
Unrivaled 
| Mouse anti Human CD1c, clone L161, recognizes CD1c. CD1c, along with CD1a and CD1b, belong to group 1 of the CD1 family of glycoproteins. These MHC-like glycoproteins serve as lipid-presenting molecules for a subset of T cells (Porcelli et al. 1989). CD1c is expressed in cortical thymocytes and a subset of B-cells (Delia et al, 1988) as well as myeloid dendritic cells (Collin, McGovern & Haniffa, 2013) |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- <0.1% Sodium Azide (NaN3)
- Immunogen
- Human thymocytes
- Purity
- >95% by SDS PAGE
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- Guaranteed for 12 months from the date of despatch or until the date of expiry, whichever comes first. Please see label for expiry date.
Store at +4°C. DO NOT FREEZE.
This product should be stored undiluted.
This product should be stored undiluted.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Flow Cytometry |  |
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| Immunohistology - Frozen | |
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| Immunoprecipitation | |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Mouse IgG1 Negative Control | MCA928 | F | 100 Tests |
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| List Price | Your Price | ||||||
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| Description | Mouse IgG1 Negative Control | ||||||
References for CD1c antibody
-
Porcelli, S. et al. (1989) Recognition of cluster of differentiation 1 antigens by human CD4-CD8-cytolytic T lymphocytes.
Nature. 341 (6241): 447-50. -
Delia, D. et al. (1988) CD1c but neither CD1a nor CD1b molecules are expressed on normal, activated, and malignant human B cells: identification of a new B-cell subset.
Blood. 72 (1): 241-7. -
Collin, M. et al. (2013) Human dendritic cell subsets.
Immunology. 140 (1): 22-30.
- UniProt
- P29017
- Entrez Gene
- CD1C
- GO Terms
- GO:0005887 integral to plasma membrane
- GO:0006955 immune response
- GO:0010008 endosome membrane
- GO:0019882 antigen processing and presentation
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