CD102 antibody | B-T1
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Mouse anti Human CD102
- Product Type
- Monoclonal Antibody
- Clone
- B-T1
- Isotype
- IgG1
- Specificity
- CD102
Antibody Quality and Performance Guarantee
| Mouse anti Human CD102 antibody, clone B-T1 recognizes human Intercellular adhesion molecule 2, also known as CD102 or ICAM-2. CD102 is a 275 amino acid ~55-65 kDa single pass type-1 transmembrane glycoprotein containing two Ig-like C2-type domains. Mouse anti Human CD102 antibody, clone B-T1 inhibits cell adhesion (Xie et al. 1995)and T cell activation and also recognizes soluble ICAM-2. |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- <0.1% sodium azide (NaN3)
- Immunogen
- ICAM-2 transfected CHO cells.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Fusion Partners
- Spleen cells from immunized BALB/c (Iffa Credo) mice were fused with cells of the X63/Ag.8653 mouse myeloma cell line.
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Flow Cytometry |  |
1/20 | 1/50 |
| Immunofluorescence | |
||
| Immunoprecipitation | |
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| Western Blotting | |
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
- Flow Cytometry
- Use 10μl of the suggested working dilution to label 106 cells in 100μl.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Mouse IgG1 Negative Control | MCA928 | F | 100 Tests |
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| List Price | Your Price | ||||||
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| Description | Mouse IgG1 Negative Control | ||||||
References for CD102 antibody
-
Xie, J. et al. (1995) Intercellular adhesion molecule-2 (CD102) binds to the leukocyte integrin CD11b/CD18 through the A domain.
J Immunol. 155 (7): 3619-28. -
Jolly, C. et al. (2007) Adhesion molecule interactions facilitate human immunodeficiency virus type 1-induced virological synapse formation between T cells.
J Virol. 81 (24): 13916-21. -
Huang, M.T. et al. (2005) Endothelial intercellular adhesion molecule (ICAM)-2 regulates angiogenesis.
Blood. 106:1636-43. -
Birdsey, G.M. et al. (2008) Transcription factor Erg regulates angiogenesis and endothelial apoptosis through VE-cadherin.
Blood. 111: 3498-506. -
Starke, R.D. et al. (2011) Endothelial von Willebrand factor regulates angiogenesis.
Blood. 117: 1071-80. -
Ishido, S. et al. (2000) Inhibition of natural killer cell-mediated cytotoxicity by Kaposi's sarcoma-associated herpesvirus K5 protein.
Immunity. 13: 365-74. -
Fricke. B. et al. (2005) Stomatin is mis-trafficked in the erythrocytes of overhydrated hereditary stomatocytosis, and is absent from normal primitive yolk sac-derived erythrocytes.
Br J Haematol.131: 265-77. -
Garbe, Y. et al. (2011) Semiallogenic fusions of MSI(+) tumor cells and activated B cells induce MSI-specific T cell responses.
BMC Cancer. 11: 410.
View The Latest Product References
-
McLaughlin, F. et al. (1998) Tumor necrosis factor (TNF)-alpha and interleukin (IL)-1beta down-regulate intercellular adhesion molecule (ICAM)-2 expression on the endothelium.
Cell Adhes Commun. 6 (5): 381-400.
- Synonyms
- ICAM-2
- RRID
- AB_321980
- UniProt
- P13598
- Entrez Gene
- ICAM2
- GO Terms
- GO:0005887 integral to plasma membrane
- GO:0005178 integrin binding
- GO:0016337 cell-cell adhesion
- GO:0050776 regulation of immune response
MCA1140
150746
164984
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