CCL24 antibody | C05-2B5
Mouse anti Human CCL24
- Product Type
- Monoclonal Antibody
- Clone
- C05-2B5
- Isotype
- IgG1
- Specificity
- CCL24
| Mouse anti Human CCL24 antibody, clone C05-2B5recognizes C-C motif chemokine 24, also known as Eotaxin-2, CK-beta-6, and MPIF-2. CCL24 is a chemokine which is induced in macophages and promotes recruitment and activation of immune cells including eosinophils, basophils, and Th2 cells by interacting with the CCR3 receptor. Therefore, CCL24 expression increases during inflammatory disease and allergic reaction, and CCL24 has been shown to perpetuate allergic reaction (Cho et al. 2016). CCL24 is involved with proinflammatory and profibrotic reactions, particularly fibrosis of the skin and lungs (Mor et al. 2019). Furthermore, CCL24 plays a role in intrahepatic fibrosis and liver damage (Segal-Salto et al. 2020). Elevated CCL24 has been associated with primary colorectal and liver metastatic tumors (Cheng et al. 2017). The purified Mouse anti Human CCL24 antibody, clone C05-2B5 (MCA6182GA) can be used as a capture antibody in a sandwich ELISA with the biotinylated Mouse anti Human CCL24 antibody, clone B01-5E2 (MCA6183B) as the detection antibody. |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Carrier Free
- Yes
- Immunogen
- E. coli derived recombinant human full length CCL24 (Val27-Ala104)
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Fusion Partners
- Cell fusion between immunized BALB/c mouse spleen cells and mouse myeloma SP2/0
- ELISA Matched Pair(s)
-
ELISA Matched Pair-Detection Antibody:
MCA6183B
ELISA Antigen-Positive Control:
PHP296
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |  |
1.0 ug/ml |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Mouse anti Human CCL24:Biotin | MCA6183B | E | 0.1 mg |
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| List Price | Your Price | ||||||
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| Description | Mouse anti Human CCL24:Biotin | ||||||
| Recombinant Human CCL24 | PHP296 | E | 10 µg | Log in | |||
| List Price | Your Price | ||||||
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| Description | Recombinant Human CCL24 | ||||||
- Synonyms
- Eotaxin-2
- UniProt
- O00175
- Entrez Gene
- CCL24
- GO Terms
- GO:0001938 positive regulation of endothelial cell proliferation
- GO:0007165 signal transduction
- GO:0005615 extracellular space
- GO:0006935 chemotaxis
- GO:0006954 inflammatory response
- GO:0006955 immune response
- GO:0007267 cell-cell signaling
- GO:0008009 chemokine activity
- GO:0030335 positive regulation of cell migration
- View More GO Terms
- GO:0030838 positive regulation of actin filament polymerization
- GO:0032855 positive regulation of Rac GTPase activity
MCA6182GA
100005296
If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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