C7 antibody | 030-113.7.5.4

Mouse anti Human C7 antibody, clone 030-113.7.5.4 does not recognie membrane bound complement membrane attack complex.
Mouse anti Human C7 antibody, clone 030-113.7.5.4 inhibits lysis of sensitised sheep erythrocytes.
Removal of Sodium Azide is recommended prior to use in functional assays. The use of EQU003 is recommended for this purpose.
Product Details
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein A
- Buffer Solution
- Borate buffered saline
- Preservative Stabilisers
- 0.1% Sodium Azide (NaN3)
- Immunogen
- Purified human C7.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
Storage Information
- Storage
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. - Guarantee
- Guaranteed until date of expiry. Please see product label.
More Information
- UniProt
- P10643 Related reagents
- Entrez Gene
- C7 Related reagents
- GO Terms
- GO:0005576 extracellular region
- GO:0005579 membrane attack complex
- GO:0006957 complement activation, alternative pathway
- GO:0006958 complement activation, classical pathway
- GO:0019835 cytolysis
- Regulatory
- For research purposes only
Applications of C7 antibody
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
ELISA | |||
Functional Assays | |||
Western Blotting |
Secondary Antibodies Available
Product Specific References
References for C7 antibody
-
Langer, F. et al. (2013) Rapid activation of monocyte tissue factor by antithymocyte globulin is dependent on complement and protein disulfide isomerase.
Blood. 121 (12): 2324-35.
Further Reading
-
Thai, C.T. & Ogata, R.T. (2004) Complement components C5 and C7: recombinant factor I modules of C7 bind to the C345C domain of C5.
J Immunol. 173 (7): 4547-52. -
Debard, A.L. et al. (2005) FcgammaRIIIb and complement component C7 codeficiency in a patient with recurrence of fulminant meningococcal septic shock.
Clin Infect Dis. 40 (11): 1679-83.