c-Met antibody | 4AT44
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Mouse anti Human c-Met
- Product Type
- Monoclonal Antibody
- Clone
- 4AT44
- Isotype
- IgG1
- Specificity
- c-Met
Antibody Quality and Performance Guarantee
| Mouse anti Human c-Met antibody, clone 4AT44 recognises c-Met, a receptor tyrosine kinase also known as hepatocyte growth factor receptor or HGFR. Binding HGF leads to autophosphorylation of c-Met and the activation of signal transduction pathways. |
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- <0.1% Sodium Azide (NaN3)
- Immunogen
- Purified recombinant protein representing the catalytic domain of human Met/HGFR.
- Approx. Protein Concentrations
- IgG concentration 0.25 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |  |
1/1,000 | |
| Western Blotting | |
1/100 | 1/500 |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- RRID
- AB_617345
- UniProt
- P08581
- Entrez Gene
- MET
- GO Terms
- GO:0005515 protein binding
- GO:0005008 hepatocyte growth factor receptor activity
- GO:0005887 integral to plasma membrane
- GO:0005524 ATP binding
- GO:0006468 protein phosphorylation
- GO:0007411 axon guidance
- GO:0008283 cell proliferation
- GO:0009925 basal plasma membrane
OBT2042
151169
159820
164658
If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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