Beta-2 Adrenergic Receptor antibody | R11E1
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|Mouse anti Human beta-2 Adrenergic Receptor antibody, clone R11E1 recognizes human beta 2 adrenergic receptor (beta2AR), a member of the G protein-coupled receptor superfamily. Beta1 and Beta2 adrenergic receptors are functionally similar but have different affinities for the ligands adrenaline and noraderenaline. B2A receptors co-exist with the B1A receptors but one subtype usually predominates. B2A receptors have a higher affinity for adrenaline and mediate the relaxation of smooth muscle including bronchus, intestine & uterus. They are located presynaptically in the nerves, where they facilitate neurotransmitter release in the brain and regulate a variety of physiological processes. Ligand binding of the B2A receptor leads to the activation of adenylyl cyclase through interaction with the GTP-binding protein Gs.|
- Target Species
- Species Cross-Reactivity
Target Species Cross Reactivity Mouse Rat
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Carrier Free
- Purified human Beta-2 adrenergic receptor.
- Approx. Protein Concentrations
- IgG concentration 1.0mg/ml
- Fusion Partners
- Cells from immunised Balb/c mice were fused with cells of the X63Ag8.653 myeloma cell line.
- For research purposes only
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
|Application Name||Verified||Min Dilution||Max Dilution|
|Immunohistology - Paraffin|
References for Beta-2 Adrenergic Receptor antibody
Patinec, A. et al. (2019) Alterations of the iNKT cell compartment in brain-injured patients.
Crit Care. 23 (1): 234.
Frielle, T. et al. (1989) Properties of the beta 1- and beta 2-adrenergic receptor subtypes revealed by molecular cloning.
Clin Chem. 35 (5): 721-5.
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"View all Anti-Human Products
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