Aquaporin 1 antibody | 1/A5F6

Product Details
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Rat Rabbit - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.1% Sodium Azide (NaN3)
0.1% Bovine Serum Albumin - Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
Storage Information
- Storage
- Store at +4oC or at -20oC if preferred.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. - Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P29972
- Entrez Gene
- AQP1
- GO Terms
- GO:0005515 protein binding
- GO:0003097 renal water transport
- GO:0005887 integral to plasma membrane
- GO:0005223 intracellular cGMP activated cation channel activity
- GO:0005267 potassium channel activity
- GO:0005737 cytoplasm
- GO:0006182 cGMP biosynthetic process
- GO:0006884 cell volume homeostasis
- GO:0046878 positive regulation of saliva secretion
- GO:0042493 response to drug
- GO:0009925 basal plasma membrane
- GO:0015079 potassium ion transmembrane transporter activity
- GO:0015168 glycerol transmembrane transporter activity
- GO:0015250 water channel activity
- GO:0015696 ammonium transport
- GO:0016324 apical plasma membrane
- GO:0020003 symbiont-containing vacuole
- GO:0021670 lateral ventricle development
- GO:0030157 pancreatic juice secretion
- GO:0030184 nitric oxide transmembrane transporter activity
- GO:0030950 establishment or maintenance of actin cytoskeleton polarity
- GO:0031526 brush border membrane
- GO:0031965 nuclear membrane
- GO:0033326 cerebrospinal fluid secretion
- GO:0034644 cellular response to UV
- GO:0035377 transepithelial water transport
- GO:0035379 carbon dioxide transmembrane transporter activity
- GO:0042383 sarcolemma
- GO:0042476 odontogenesis
- GO:0043066 negative regulation of apoptosis
- GO:0045766 positive regulation of angiogenesis
- GO:0048146 positive regulation of fibroblast proliferation
- GO:0051739 ammonia transmembrane transporter activity
- GO:0070301 cellular response to hydrogen peroxide
- GO:0071260 cellular response to mechanical stimulus
- GO:0071280 cellular response to copper ion
- GO:0071288 cellular response to mercury ion
- GO:0071300 cellular response to retinoic acid
- GO:0071320 cellular response to cAMP
- GO:0071456 cellular response to hypoxia
- GO:0071472 cellular response to salt stress
- GO:0071474 cellular hyperosmotic response
- GO:0071549 cellular response to dexamethasone stimulus
- GO:0071732 cellular response to nitric oxide
- GO:0085018 maintenance of symbiont-containing vacuole via substance secreted by host
- Regulatory
- For research purposes only
Applications of Aquaporin 1 antibody
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
ELISA | 1/1000 | 1/20000 | |
Immunofluorescence | |||
Immunohistology - Frozen | 1/500 | 1/1000 | |
Immunohistology - Paraffin 1 | 1/500 | 1/1000 | |
Western Blotting | 1/1000 | 1/5000 |
- 1This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.Sodium citrate buffer pH 6.0 is recommended for this purpose.
- Histology Positive Control Tissue
- Kidney
Secondary Antibodies Available
Product Specific References
References for Aquaporin 1 antibody
-
Nagy G et al. (2002) Development and characterisation of a monoclonal antibody family against aquaporin 1 (AQP1) and aquaporin 4 (AQP4).
Pathol Oncol Res. 8 (2): 115-24. -
Bódis, B. et al. (2001) Active water selective channels in the stomach: investigation of aquaporins after ethanol and capsaicin treatment in rats.
J Physiol Paris. 95 (1-6): 271-5. -
Francone, V.P. et al (2010) Signaling from the secretory granule to the nucleus: Uhmk1 and PAM.
Mol Endocrinol. 24: 1543-58. -
Felszeghy, S. et al (2004) Expression of aquaporin isoforms during human and mouse tooth development.
Arch Oral Biol. 49: 247-57. -
Ripoche, P. et al. (2004) Human Rhesus-associated glycoprotein mediates facilitated transport of NH(3) into red blood cells.
Proc Natl Acad Sci U S A. 101: 17222-7. -
Lupp, A. et al. (2010) Immunohistochemical identification of the PTHR1 parathyroid hormone receptor in normal and neoplastic human tissues.
Eur J Endocrinol. 162: 979-86. -
Pannabecker, T.L. et al. (2008) Quantitative analysis of functional reconstructions reveals lateral and axial zonation in the renal inner medulla.
Am J Physiol Renal Physiol. 294: F1306-14. -
Thiele, S. et al. (2007) A disruptive mutation in exon 3 of the GNAS gene with albright hereditary osteodystrophy, normocalcemic pseudohypoparathyroidism, and selective long transcript variant Gsalpha-L deficiency.
J Clin Endocrinol Metab. 92: 1764-8. -
Antonelou, M.H. et al. (2011) Oxidative stress-associated shape transformation and membrane proteome remodeling in erythrocytes of end stage renal disease patients on hemodialysis.
J Proteomics. 74: 2441-52. -
Arnaud, L. et al. (2010) A functional AQP1 allele producing a Co(a-b-) phenotype revises and extends the Colton blood group system.
Transfusion. 50: 2106-16. -
Saison, C. et al. (2012) A new AQP1 null allele identified in a Gypsy woman who developed an anti-CO3 during her first pregnancy.
Vox Sang. 103: 137-44. -
Ferré-Dolcet, L. et al. (2019) Uterine and placental specific localization of AQP2 and AQP8 is related with changes of serum progesterone levels in pregnant queens.
Theriogenology. 142: 149-57. -
Hsu, K. et al. (2017) Adaptable interaction between aquaporin-1 and band 3 reveals a potential role of water channel in blood CO2 transport.
FASEB J. 31 (10): 4256-64.
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