Heparin/Heparan sulfate antibody | T320.11
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|Mouse anti Heparin/Heparan sulfate, clone T320.11, recognizes the chemically related αβ-linked glycosaminoglycans heparin and heparan sulfate.
Both heparin and heparan sulfate are composed of alternating sequences of glucosamine and uronic acid with heparin being the more heavily sulfated polymer (Gallagher & Walker, 1985).
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein A from ascites
- Buffer Solution
- Phosphate Buffered Saline
- Preservative Stabilisers
- 0.1% Sodium Azide (NaN3)
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- For research purposes only
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
|Application Name||Verified||Min Dilution||Max Dilution|
References for Heparin/Heparan sulfate antibody
Shibata, S. et al. (1993) Monoclonal antibodies to heparan sulfate inhibit the formation of thrombin-antithrombin III complexes.
Clin Immunol Immunopathol. 67 (3 Pt 1): 264-72.
Coles, C.H. et al. (2011) Proteoglycan-specific molecular switch for RPTPσ clustering and neuronal extension.
Science. 332 (6028): 484-8.
Kato, R. et al. (2017) Heparan sulfate storage in the cardiac conduction system triggers atrioventricular block.
Brain Dev. 39 (5): 418-421.
Danzberger, J. et al. (2018) Glycan distribution and density in native skin's stratum corneum.
Skin Res Technol. 24 (3): 450-8.
Gallagher, J.T. & Walker, A. (1985) Molecular distinctions between heparan sulphate and heparin. Analysis of sulphation patterns indicates that heparan sulphate and heparin are separate families of N-sulphated polysaccharides.
Biochem J. 230 (3): 665-74.
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