AMPK Alpha 1/2 antibody | 84.1
AMPK may play an important role in the control of type 2 diabetes and metabolic syndromes. Recent studies suggest that AMPK functions as a suppressor of cell proliferation of both malignant and normal cells.
Product Details
- Target Species
- Drosophila
- Species Cross-Reactivity
-
Target Species Cross Reactivity Vertebrates Expected from Sequence Human Expected from Sequence Mouse Expected from Sequence Rat Expected from Sequence - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.09% Sodium Azide (NaN3) - Carrier Free
- Yes
- Immunogen
- 29 amino acid peptide within the N-terminal catalytic domain of Drosophila AMPK alpha.
- Approx. Protein Concentrations
- IgG concentration 1.0mg/ml
Storage Information
- Storage
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. - Guarantee
- 12 months from date of despatch
More Information
- UniProt
- Q13131
- Entrez Gene
- PRKAA1
- GO Terms
- GO:0000187 activation of MAPK activity
- GO:0005515 protein binding
- GO:0001666 response to hypoxia
- GO:0005829 cytosol
- GO:0004691 cAMP-dependent protein kinase activity
- GO:0046872 metal ion binding
- GO:0005524 ATP binding
- GO:0006633 fatty acid biosynthetic process
- GO:0006695 cholesterol biosynthetic process
- GO:0007050 cell cycle arrest
- GO:0008286 insulin receptor signaling pathway
- GO:0045542 positive regulation of cholesterol biosynthetic process
- GO:0045768 positive regulation of anti-apoptosis
- GO:0046318 negative regulation of glucosylceramide biosynthetic process
- GO:0046320 regulation of fatty acid oxidation
- Regulatory
- For research purposes only
Applications of AMPK Alpha 1/2 antibody
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
ELISA | |||
Immunofluorescence | |||
Immunohistology - Frozen | |||
Immunoprecipitation | |||
Western Blotting | 1/100 | 1/1000 |
- Western Blotting
- MCA2673GA detects a band of approximately 63kDa in rat brain cell lysates.
Secondary Antibodies Available
Fluorescent Spectraviewer
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