Anthrax antibody | 7821
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Mouse anti Anthrax
- Product Type
- Monoclonal Antibody
- Clone
- 7821
- Isotype
- IgG2b
- Specificity
- Anthrax
Antibody Quality and Performance Guarantee
| Mouse anti anthrax antibody, clone 7821 recognizes the protective antigen (PA) of Bacillus anthracis, also known as the toxin binding protein, a component, along with edema factor and lethal factor, of the anthrax toxin. Protective antigen binds to the cell surface receptor, Anthrax toxin receptor, also known as tumor endothelial marker 8 and mediates transfer of edema factor and lethal factor to the cytosol where they enzymatically modify a number of substrates impairing cellular function (Bradley et al. 2001). |
- Target Species
- Bacterial
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein A from ascites
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.1% Sodium Azide (NaN3)
- Approx. Protein Concentrations
- IgG concentration 0.1 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |  |
1/20 | 1/200 |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- RRID
- AB_620545
- UniProt
- P13423
- Entrez Gene
- pxo1_110
- GO Terms
- GO:0005515 protein binding
- GO:0046872 metal ion binding
- GO:0005615 extracellular space
- GO:0009405 pathogenesis
OBT0703
150903
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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