Cell proliferation, motility, and survival are tightly regulated by a network of signaling pathways, preventing uncontrolled cell division. A cell can become cancerous when it undergoes a genetic or epigenetic mutation that allows it to escape this regulation and can then divide rapidly. Unraveling the complex fabric of signaling pathways is crucial for cancer research, and for developing new, life-changing therapies for patients.
We have compiled key proteins involved in the EGF R signaling pathway into one handy poster you can download for your reference.
Understanding mTOR signaling provides a basis for developing mTOR inhibitors, and inhibitors of components within the wider signaling pathway. Inhibition of the mTOR pathway is relevant for cancer, obesity, diabetes, and even aging. Uncover the proteins involved.
An overview of acute myeloid leukemia (AML) risk stratifications, frequency, and types of genetic alterations, as well as current therapies.
Covers the most common genetic mutations resulting in the development of melanomas, highlights the progression from an aberrant melanocyte to a metastatic melanoma and treatment approaches.
An overview of the mitochondrial fusion-division cycle, and the fusion and division machinery in mammalian cells, yeast, and algae.