We have compiled key proteins involved in the EGF R signaling pathway into one handy poster you can download for your reference.Learn more
Learn about the conflicting nature of R-loops, a trending area of cancer research.Learn more
SnapShot from Cell Press: Acute Myeloid Leukemia posterDownload PDF
The “SnapShot from Cell Press: Acute Myeloid Leukemia” poster describes the most common gene mutations underlying Acute Myeloid Leukemia (AML). These include mutations in genes encoding cell signaling proteins such as the PTEN phosphatase and the CD135/FLT3 and CD117/KIT receptor tyrosine kinases. Mutations in transcription factors, like p53 and NPM1, and in epigenetic modifiers, such as the DNA methyltransferase DNMT3A, have also been reported. For a complete overview of the frequency of common gene mutations, AML risk stratifications and current therapies, download or request the AML poster.
In order to make it easier for you to select reagents for AML research, we have grouped antibodies against the critical proteins mentioned on the poster together in a convenient selector tool. These include our range of p53 antibodies, mTOR and MEK1 PrecisionAb Western blot validated antibodies. The PrecisionAb label is reserved for antibodies that meet the strictest performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range.