SnapShot from Cell Press: Acute Myeloid Leukemia posterDownload SnapShot PDF
The “SnapShot from Cell Press: Acute Myeloid Leukemia” poster describes the most common gene mutations underlying Acute Myeloid Leukemia (AML). These include mutations in genes encoding cell signaling proteins such as the PTEN phosphatase and the CD135/FLT3 and CD117/KIT receptor tyrosine kinases. Mutations in transcription factors, like p53 and NPM1, and in epigenetic modifiers, such as the DNA methyltransferase DNMT3A, have also been reported. For a complete overview of the frequency of common gene mutations, AML risk stratifications and current therapies, download or request the AML poster.
In order to make it easier for you to select reagents for AML research, we have grouped antibodies against the critical proteins mentioned on the poster together in a convenient selector tool. These include our range of p53 antibodies, mTOR and MEK1 PrecisionAb Western blot validated antibodies. The PrecisionAb label is reserved for antibodies that meet the strictest performance criteria within Bio-Rad's ongoing antibody validation programme. To learn more about how we validate our PrecisionAb range visit our Validated Western Blotting Antibodies page.
Browse our range of antibodies for Acute Myeloid Leukemia below. Please use the filters to sort the attributes in the table below in order to find the antibody that fits your exact requirements. If you need any further assistance please do not hesitate to contact us.