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Measuring adaptive and innate immune responses in ruminants
Does your research require assaying immune responses in cattle and sheep?
Do you seek to better define cell populations in ruminants?
The ability to identify immunological correlates of protection is a key element of vaccine development. This is challenging in farmed ruminants due to the relative lack of reagents to fully characterize cattle and sheep immune responses compared to laboratory rodents. To help address this gap in capability, researchers at the Moredun Research Institute and The Roslin Institute at the University of Edinburgh have been collaborating on a project specifically to develop and characterize immunological reagents for cattle and sheep to underpin vaccine research.
Watch the webinar to discover more about this project. The background to the research work is described and the data presented show the highlights of the work carried out over the last three years. The advances made on the characterization of myeloid cell subsets in peripheral blood and methods to identify CD4+ve T cells that produce IL-17 are focused on in detail.
This talk is of interest to researchers seeking to:
Presented by Professor Gary Entrican: Principal Research Scientist at at the Moredun Research Institute.
Speaker Biography: Professor Gary Entrican
Gary Entrican is a Principal Research Scientist at Moredun and holds an Honorary Professorship within the College of Medicine and Veterinary Medicine, University of Edinburgh. He graduated with BSc Hons in Immunology from the University of Glasgow, where he also conducted his PhD in Immunology. He joined Moredun in 1986 working on immune regulation in sheep.
Gary's immunological skills are in the areas of ruminant cellular immunology, cytokine biology and the understanding of host-pathogen interactions during infection.
The ultimate aim of his research is to identify immunological correlates of protection that underpin vaccine design and implementation of disease control strategies.