Cytomegalovirus gB Late Cytoplasmic Antigen antibody | hCMV34
|Mouse anti Cytomegalovirus gB Late Cytoplasmic Antigen antibody, clone hCMV34 detects cytomegalovirus glycoprotein B late cytoplasmic antigen. Cytomegalovirus is an enveloped double stranded DNA virus which in humans (HCMV) is commonly known as human herpesvirus 5 (HHV-5).
Glycoprotein B (gB) is the main antigenic protein within the envelope of HCMV. It is required for HCMV mediated membrane fusion along with the gH / gL complex. The unprocessed precursor of HCMV gB is 906 amino acids in length, with a MW of approximately 100kDa.
Mouse anti Cytomegalovirus gB Late Cytoplasmic Antigen antibody, clone hCMV34 does not react with HSV, VZV or EBV. Reacts with MRC-5 infected cells, but not uninfected cells.
Mouse anti Cytomegalovirus gB Late Cytoplasmic Antigen antibody, clone hCMV34 has been used successfully to demonstrate presence of CMV in infected cells by immunofluorescence on paraformaldehyde fixed cell cultures (González-Sánchez et al 2015).
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Carrier Free
- Native cytomeglaovirus extracts from infected human cells..
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- For research purposes only
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
|Application Name||Verified||Min Dilution||Max Dilution|
|Immunofluorescence||0.02 µg/slide||1 µg/slide|
|Immunohistology - Frozen 1|
- 1Reactive only in acetone fixed CMV infected cells or frozen sections.
References for Cytomegalovirus gB Late Cytoplasmic Antigen antibody
González-Sánchez HM et al. (2015) Effects of cytomegalovirus infection in human neural precursor cells depend on their differentiation state.
J Neurovirol. 21 (4): 346-57.
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"View all Anti-Viral Products
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