CD2 antibody | OX-34
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Mouse anti Rat CD2
- Product Type
- Monoclonal Antibody
|Mouse anti Rat CD2 antibody, clone OX-34 recognizes a determinant on thymocytes and peripheral T-cells but it does not bind to B cells or peritoneal macrophages. The antigen recognized by this antibody is a 50-54 kDa glycoprotein, homolog of the human CD2 antigen (Williams et al. 1987).|
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% sodium azide (NaN3)
- Carrier Free
- Activated rat T helper cells.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Fusion Partners
- Spleen cells from immunised BALB/c mice were fused with cells of the NS1 mouse myeloma cell line.
- For research purposes only
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
|Application Name||Verified||Min Dilution||Max Dilution|
|Immunohistology - Frozen|
|Immunohistology - Paraffin 1|
- 1We recommend the use of PLP fixation for optimal results, see Whiteland et al.
- Flow Cytometry
- Use 10μl of the suggested working dilution to label 106 cells in 100μl
|Description||Product Code||Applications||Pack Size||List Price||Your Price||Quantity|
|Mouse IgG2a Negative Control||MCA1210||F||100 Tests||Log in|
|List Price||Your Price|
|Description||Mouse IgG2a Negative Control|
References for CD2 antibody
Williams, A.F. et al. (1987) Similarities in sequences and cellular expression between rat CD2 and CD4 antigens.
J Exp Med. 165 (2): 368-80.
Barclay, A.N. (1981) The localization of populations of lymphocytes defined by monoclonal antibodies in rat lymphoid tissues.
Immunology. 42 (4): 593-600.
Whiteland, J.L. et al. (1995) Immunohistochemical detection of T-cell subsets and other leukocytes in paraffin-embedded rat and mouse tissues with monoclonal antibodies.
J Histochem Cytochem. 43 (3): 313-20.
Baker, S.C. et al. (2011) Cellular Integration and Vascularisation Promoted by a Resorbable, Particulate-Leached, Cross-Linked Poly(ε-caprolactone) Scaffold.
Macromol Biosci. 11: 618-27.
Romani, P. et al. (2009) Cell survival and polarity of Drosophila follicle cells require the activity of ecdysone receptor B1 isoform.
Genetics. 181: 165-75.
Stybayeva, G. et al. (2010) Lensfree holographic imaging of antibody microarrays for high-throughput detection of leukocyte numbers and function.
Anal Chem. 82: 3736-44.
Bastock, R. et al. (2003) Strabismus is asymmetrically localised and binds to Prickle and Dishevelled during Drosophila planar polarity patterning.
Development. 130: 3007-14.
Brückner, K. et al. (2000) Glycosyltransferase activity of Fringe modulates Notch-Delta interactions.
Nature. 406: 411-5.
View The Latest Product References
Liversidge, J. et al. (2002) Nitric oxide mediates apoptosis through formation of peroxynitrite and Fas/Fas-ligand interactions in experimental autoimmune uveitis.
Am J Pathol. 160: 905-16.
Sarpal, R. et al. (2012) Mutational analysis supports a core role for Drosophila α-catenin in adherens junction function.
J Cell Sci. 125: 233-45.
Zhang, H. et al. (2011) Basic residues in the T-cell receptor ζ cytoplasmic domain mediate membrane association and modulate signaling.
Proc Natl Acad Sci U S A. 108: 19323-8.
Heck, B.W. et al. (2012) The transcriptional corepressor SMRTER influences both Notch and ecdysone signaling during Drosophila development.
Biol Open. 1 (3): 182-96.
Clark, I.B. et al. (2011) Fibroblast growth factor signalling controls successive cell behaviours during mesoderm layer formation in Drosophila.
Development. 138: 2705-15.
Domanitskaya, E. and Schüpbach, T. (2012) CoREST acts as a positive regulator of Notch signaling in the follicle cells of Drosophila melanogaster.
J Cell Sci. 125: 399-410.
Dragovic, R.A. et al. (2015) Isolation of syncytiotrophoblast microvesicles and exosomes and their characterisation by multicolour flow cytometry and fluorescence Nanoparticle Tracking Analysis.
Methods. 87: 64-74.
Zecca, M. & Struhl, G. (2021) A unified mechanism for the control of Drosophila. wing growth by the morphogens Decapentaplegic and Wingless.
PLoS Biol. 19 (3): e3001111.
- E-Rosette Receptor
- Entrez Gene
- GO Terms
- GO:0001948 glycoprotein binding
- GO:0003823 antigen binding
- GO:0016021 integral to membrane
- GO:0005615 extracellular space
- GO:0030971 receptor tyrosine kinase binding
- GO:0009986 cell surface
- GO:0016337 cell-cell adhesion
- GO:0019901 protein kinase binding
- GO:0042110 T cell activation
- View More GO Terms
- GO:0042803 protein homodimerization activity
- GO:0043234 protein complex
- GO:0043621 protein self-association
- GO:0044214 fully spanning the plasma membrane
- GO:0045121 membrane raft
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"View all Anti-Rat Products
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