CD68 antibody | FA-11

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Rat anti Mouse CD68:Alexa Fluor® 488

CD68 antibody, clone FA-11 recognizes mouse macrosialin which is a homolog of human CD68, which is classified as a unique scavenger receptor (ScR) family member. CD68 is considered a pan macrophage marker expressed on the intracellular lysosomes of tissue macrophages.

Rat anti Mouse CD68:Alexa Fluor® 647

CD68 antibody, clone FA-11 recognizes mouse macrosialin which is a homolog of human CD68, which is classified as a unique scavenger receptor (ScR) family member. CD68 is considered a pan macrophage marker expressed on the intracellular lysosomes of tissue macrophages.

Rat anti Mouse CD68:Biotin

CD68 antibody, clone FA-11 recognizes mouse macrosialin which is a homolog of human CD68, which is classified as a unique scavenger receptor (ScR) family member. CD68 is considered a pan macrophage marker expressed on the intracellular lysosomes of tissue macrophages.

Rat anti Mouse CD68:FITC

CD68 antibody, clone FA-11 recognizes mouse macrosialin which is a homolog of human CD68, which is classified as a unique scavenger receptor (ScR) family member. CD68 is considered a pan macrophage marker expressed on the intracellular lysosomes of tissue macrophages.

Rat anti Mouse CD68:Endotoxin Low

CD68 antibody, clone FA-11 recognizes mouse macrosialin which is a homolog of human CD68, which is classified as a unique scavenger receptor (ScR) family member. CD68 is considered a pan macrophage marker expressed on the intracellular lysosomes of tissue macrophages.

Rat anti Mouse CD68

CD68 antibody, clone FA-11 recognizes mouse macrosialin which is a homolog of human CD68, which is classified as a unique scavenger receptor (ScR) family member. CD68 is considered a pan macrophage marker expressed on the intracellular lysosomes of tissue macrophages.

Rat anti Mouse CD68:RPE

CD68 antibody, clone FA-11 recognizes mouse macrosialin which is a homolog of human CD68, which is classified as a unique scavenger receptor (ScR) family member. CD68 is considered a pan macrophage marker expressed on the intracellular lysosomes of tissue macrophages.

Rat anti Mouse CD68:Alexa Fluor® 700

CD68 antibody, clone FA-11 recognizes mouse macrosialin which is a homolog of human CD68, which is classified as a unique scavenger receptor (ScR) family member. CD68 is considered a pan macrophage marker expressed on the intracellular lysosomes of tissue macrophages.

Product Type
Monoclonal Antibody
Clone
FA-11
Isotype
IgG2a
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
MCA1957A488T F* 25 Tests/0.25ml
MCA1957A488 F* 100 Tests/1ml
MCA1957A647T F* 25 Tests/0.25ml
MCA1957A647 F* 100 Tests/1ml
MCA1957BT C F 25 µg
MCA1957B C F 0.1 mg
MCA1957FT F* 25 µg
MCA1957FA F* 50 µg
MCA1957F F* 0.1 mg
MCA1957EL C F* IF IP P* WB* 0.5 mg
MCA1957T C F* IF IP P* WB* 25 µg
MCA1957GA C F* IF IP P* WB* 0.1 mg
MCA1957 C F* IF IP P* WB* 0.25 mg
MCA1957PET F* 25 Tests
MCA1957PE F* 100 Tests
MCA1957A700T F* 25 Tests/0.25ml
MCA1957A700 F* 100 Tests/1ml
Rat anti Mouse CD68 antibody, clone FA-11 recognizes mouse macrosialin, a heavily glycosylated transmembrane protein and murine homolog of human CD68, which is classified as a unique scavenger receptor (ScR) family member, due to the presence of a lysosome associated membrane protein (LAMP)-like domain.

CD68 is considered a pan macrophage marker, predominantly expressed on the intracellular lysosomes of tissue macrophages/monocytes, including Kupffer cells, microglia, histiocytes and osteoclasts, and is expressed to a lesser extent by dendritic cells and peripheral blood granulocytes.

CD68 is expressed by many tumor types including some B cell lymphomas, blastic NK lymphomas, melanomas, granulocytic (myeloid) sarcomas, hairy cell leukemias, and renal, urinary and pancreatic tumors, and can be used in cancer studies to demonstrate the presence/localization of macrophages.

Rat anti mouse CD68 antibody, clone FA-11, has been used in many mouse models for the identification of CD68 in immunohistochemical studies, using both frozen and paraffin-embedded tissues (Masaki et al. 2003) and (Devey et al. 2009).

Rat anti mouse CD68 antibody, clone FA-11 can be used in flow cytometry to detect intracellular CD68, following permeabilization, and can detect surface macrosialin at low levels in resident mouse peritoneal macrophages which can be enhanced with thioglycollate stimulation.

Product Details

Target Species
Mouse
Product Form
Purified IgG conjugated to Alexa Fluor® 488 - liquid
Product Form
Purified IgG conjugated to Alexa Fluor® 647 - liquid
Product Form
Purified IgG conjugated to Biotin - liquid
Product Form
Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
Product Form
Purified IgG - liquid
Product Form
Purified IgG - liquid
Product Form
Purified IgG conjugated to R. Phycoerythrin (RPE) - lyophilized
Product Form
Purified IgG conjugated to Alexa Fluor® 700 - liquid
Reconstitution
Pack Size: 25 Tests
Reconstitute in 0.25 ml disilled water
Pack Size: 100 Tests
Reconstitute with 1.0 ml distilled water
Preparation
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Preparation
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Preparation
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Preparation
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Preparation
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Preparation
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Preparation
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Preparation
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution
Phosphate buffered saline
Buffer Solution
Phosphate buffered saline
Buffer Solution
Phosphate buffered saline
Buffer Solution
Phosphate buffered saline
Buffer Solution
Phosphate buffered saline
Buffer Solution
Phosphate buffered saline
Buffer Solution
Phosphate buffered saline
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09%Sodium Azide
1%Bovine Serum Albumin
Preservative Stabilisers
0.09%Sodium Azide
1%Bovine Serum Albumin
Preservative Stabilisers
0.09%Sodium Azide
1%Bovine Serum Albumin
Preservative Stabilisers
0.09%Sodium Azide
1%Bovine Serum Albumin
Preservative Stabilisers
None present
Preservative Stabilisers
0.09%Sodium Azide
Preservative Stabilisers
0.09%Sodium Azide
1%Bovine Serum Albumin
5%Sucrose
Preservative Stabilisers
0.09%Sodium Azide
1%Bovine Serum Albumin
Carrier Free
Yes
Carrier Free
Yes
Immunogen
Purified Concanavalin A acceptor glycoprotein from P815 cell line.
Approx. Protein Concentrations
IgG concentration 0.05 mg/ml
Approx. Protein Concentrations
IgG concentration 0.05 mg/ml
Approx. Protein Concentrations
IgG concentration 0.1mg/ml
Approx. Protein Concentrations
IgG concentration 0.1mg/ml
Approx. Protein Concentrations
IgG concentration 1.0mg/ml
Approx. Protein Concentrations
Pack Size: 25 µg, 0.25 mg
IgG concentration 1.0mg/ml
Pack Size: 0.1 mg
IgG concentration 1.0 mg/ml
Approx. Protein Concentrations
IgG concentration 0.05 mg/ml

Storage Information

Storage
Store at +4oC or at -20oC if preferred.

This product should be stored undiluted.

Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light.

Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage
Store at +4oC or at -20oC if preferred.

This product should be stored undiluted.

Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light.

Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage
Store at +4oC or at -20oC if preferred.

This product should be stored undiluted.

Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage
Store at +4oC or at -20oC if preferred.

This product should be stored undiluted.

Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light.

Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage
Store at -20oC only.

This product should be stored undiluted.

Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage
Store at +4oC or at -20oC if preferred.

This product should be stored undiluted.

Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage
Store at +4oC.

DO NOT FREEZE.

This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage
Store at +4oC or at -20oC if preferred.

This product should be stored undiluted.

Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light.

Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Guarantee
18 months from date of despatch.
Guarantee
18 months from date of despatch.
Guarantee
18 months from date of despatch.
Guarantee
18 months from date of despatch.
Guarantee
18 months from date of despatch.
Guarantee
18 months from date of despatch.
Guarantee
12 months from date of reconstitution.
Guarantee
18 months from date of despatch.

More Information

UniProt
P31996 Related reagents
Entrez Gene
Cd68 Related reagents
GO Terms
GO:0005886 plasma membrane
GO:0016021 integral to membrane
GO:0005765 lysosomal membrane
GO:0010008 endosome membrane
Acknowledgements
This product is provided under an intellectual property licence from Life Technologies Corporation. The transfer of this product is contingent on the buyer using the purchase product solely in research, excluding contract research or any fee for service research, and the buyer must not sell or otherwise transfer this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; (c) manufacturing or quality assurance or quality control, or (d) resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad CA 92008 USA or outlicensing@thermofisher.com
Acknowledgements
This product is provided under an intellectual property licence from Life Technologies Corporation. The transfer of this product is contingent on the buyer using the purchase product solely in research, excluding contract research or any fee for service research, and the buyer must not sell or otherwise transfer this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; (c) manufacturing or quality assurance or quality control, or (d) resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad CA 92008 USA or outlicensing@thermofisher.com
Acknowledgements
This product is provided under an intellectual property licence from Life Technologies Corporation. The transfer of this product is contingent on the buyer using the purchase product solely in research, excluding contract research or any fee for service research, and the buyer must not sell or otherwise transfer this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; (c) manufacturing or quality assurance or quality control, or (d) resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad CA 92008 USA or outlicensing@thermofisher.com
Regulatory
For research purposes only

Applications of CD68 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Flow Cytometry 1 Neat 1/10
Flow Cytometry 1 Neat 1/10
Flow Cytometry
Immunohistology - Frozen 1/10
Flow Cytometry 1 Neat 1/10
Flow Cytometry 1 1/50 1/100
Immunofluorescence
Immunohistology - Frozen
Immunohistology - Paraffin 2
Immunoprecipitation
Western Blotting 3
Flow Cytometry 1 1/50 1/100
Immunofluorescence
Immunohistology - Frozen
Immunohistology - Paraffin 2
Immunoprecipitation
Western Blotting 3
Flow Cytometry 1 Neat
Flow Cytometry 1 Neat 1/10
  1. 1 Membrane permeabilisation is required for this application. Bio-Rad recommends the use of Leucoperm™ (Product Code BUF09) for this purpose.
    The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors. This may be reduced by using SeroBlock FcR (Product Code BUF041).
  1. 1 Membrane permeabilisation is required for this application. Bio-Rad recommends the use of Leucoperm™ (Product Code BUF09) for this purpose.
    The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors. This may be reduced by using SeroBlock FcR (Product Code BUF041).
  1. 1 Membrane permeabilisation is required for this application. Bio-Rad recommends the use of Leucoperm™ (Product Code BUF09) for this purpose.
    The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors. This may be reduced by using SeroBlock FcR ( Product Code BUF041).
  1. 1 Membrane permeabilisation is required for this application. Bio-Rad recommends the use of Leucoperm™ (Product Code BUF09) for this purpose.
  2. 2This product may require antigen retrieval using heat treatment prior to staining of paraffin sections.Sodium citrate buffer pH 6.0 is recommended for this purpose. See Martin-Manso for details. Staining has also been achieved without antigen retrieval, see Lu for details.
  3. 3 Non-reducing conditions recommended.
  1. 1 Membrane permeabilisation is required for this application. Bio-Rad recommends the use of Leucoperm™ (Product Code BUF09) for this purpose.
  2. 2This product may require antigen retrieval using heat treatment prior to staining of paraffin sections.Either sodium citrate buffer or Tris/EDTA buffer may be used for this purpose. See Martin-Manso for details. Staining has also been achieved without antigen retrieval, see Lu for details.
  3. 3 Non-reducing conditions recommended.
  1. 1 Membrane permeabilisation is required for this application. Bio-Rad recommends the use of Leucoperm™ (Product Code BUF09) for this purpose.
    The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors. This may be reduced by using SeroBlock FcR (Product Code BUF041).
  1. 1 Membrane permeabilisation is required for this application. Bio-Rad recommends the use of Leucoperm™ (Product Code BUF09) for this purpose.
    The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors. This may be reduced by using SeroBlock FcR (Product Code BUF041).
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Flow Cytometry
Use 10ul of the suggested working dilution to label 106 cells in 100ul. Recommended protocols are available Here
Flow Cytometry
Use 10ul of the suggested working dilution to label 106 cells in 100ul. Recommended protocols are available Here
Flow Cytometry
Use 10ul of the suggested working dilution to label 106 cells in 100ul. Recommended protocols are available Here
Flow Cytometry
Use 10ul of the suggested working dilution to label 106 cells in 100ul. Recommended protocols are available Here
Flow Cytometry
Use 10ul of the suggested working dilution to label 1x106 cells in 100ul.
Flow Cytometry
Use 10ul of the suggested working dilution to label 106 cells in 100ul. Recommended protocols are available Here
Flow Cytometry
Use 10ul of the suggested working dilution to label 106 cells in 100ul. Recommended protocols are available Here
Flow Cytometry
Use 10ul of the suggested working dilution to label 106 cells in 100ul. Recommended protocols are available Here

Secondary Antibodies Available

Description Product Code Pack Size Applications List Price Quantity
Goat anti Rat IgG:Alk. Phos. (Mouse Adsorbed) STAR131A 1 ml C E P WB
Goat anti Rat IgG:Biotin (Mouse Adsorbed) STAR131B 0.5 mg C E IF P WB
Rabbit F(ab')2 anti Rat IgG:Dylight®800 STAR16D800GA 0.1 mg F IF WB
Rabbit F(ab')2 anti Rat IgG:FITC STAR17B 1 mg F
Rabbit F(ab')2 anti Rat IgG:HRP STAR21B 1 mg C E P RE
Goat F(ab')2 anti Rat IgG:FITC (Mouse Adsorbed) STAR69 0.5 ml F
Goat anti Rat IgG:DyLight®649 (Mouse Adsorbed) STAR71D649GA 0.1 mg F IF
Goat anti Rat IgG:Dylight®800 (Mouse Adsorbed) STAR71D800GA 0.1 mg F IF WB
Goat anti Rat IgG:HRP (Mouse Adsorbed) STAR72 0.5 mg C E P
Goat F(ab')2 anti Rat IgG:RPE (Mouse Adsorbed) STAR73 0.5 ml F
Goat anti Rat IgG:Alk. Phos. (Mouse Adsorbed) STAR131A 1 ml C E P WB
Goat anti Rat IgG:Biotin (Mouse Adsorbed) STAR131B 0.5 mg C E IF P WB
Rabbit F(ab')2 anti Rat IgG:Dylight®800 STAR16D800GA 0.1 mg F IF WB
Rabbit F(ab')2 anti Rat IgG:FITC STAR17B 1 mg F
Rabbit F(ab')2 anti Rat IgG:HRP STAR21B 1 mg C E P RE
Goat F(ab')2 anti Rat IgG:FITC (Mouse Adsorbed) STAR69 0.5 ml F
Goat anti Rat IgG:DyLight®649 (Mouse Adsorbed) STAR71D649GA 0.1 mg F IF
Goat anti Rat IgG:Dylight®800 (Mouse Adsorbed) STAR71D800GA 0.1 mg F IF WB
Goat anti Rat IgG:HRP (Mouse Adsorbed) STAR72 0.5 mg C E P
Goat F(ab')2 anti Rat IgG:RPE (Mouse Adsorbed) STAR73 0.5 ml F

Negative Isotype Controls Available

Description Product Code Pack Size Applications List Price Quantity
Rat IgG2a Negative Control:Alexa Fluor® 488 MCA1212A488 100 Tests/1ml F
Rat IgG2a Negative Control:Alexa Fluor® 647 MCA1212A647 100 Tests/1ml F
Rat IgG2a Negative Control:FITC MCA1212F 100 Tests F
Rat IgG2a Negative Control:Low Endotoxin MCA1212EL 0.5 mg F
Rat IgG2a Negative Control MCA1212 1 ml E F
Rat IgG2a Negative Control:RPE MCA1212PE 100 Tests F
Rat IgG2a Negative Control:Alexa Fluor® 700 MCA1212A700 100 Tests/1ml F

Useful Reagents Available

Description Product Code Pack Size Applications List Price Quantity
Leucoperm™ BUF09 50 Tests F
Mouse Seroblock FcR BUF041A 0.1 mg F
Mouse Seroblock FcR BUF041B 0.5 mg F
Leucoperm™ BUF09 50 Tests F
Mouse Seroblock FcR BUF041A 0.1 mg F
Mouse Seroblock FcR BUF041B 0.5 mg F
Leucoperm™ BUF09 50 Tests F
Mouse Seroblock FcR BUF041A 0.1 mg F
Mouse Seroblock FcR BUF041B 0.5 mg F
Leucoperm™ BUF09 50 Tests F
Mouse Seroblock FcR BUF041A 0.1 mg F
Mouse Seroblock FcR BUF041B 0.5 mg F
Antigen Retrieval Buffer, pH8.0 BUF025A 500 ml P
Antigen Retrieval Buffer, pH8.0 BUF025C 50 ml P
Leucoperm™ BUF09 50 Tests F
Antigen Retrieval Buffer, pH8.0 BUF025A 500 ml P
Antigen Retrieval Buffer, pH8.0 BUF025C 50 ml P
Leucoperm™ BUF09 50 Tests F
Leucoperm™ BUF09 50 Tests F
Mouse Seroblock FcR BUF041A 0.1 mg F
Mouse Seroblock FcR BUF041B 0.5 mg F
Leucoperm™ BUF09 50 Tests F

Application Based External Images

Flow Cytometry

Immunofluorescence

Immunohistology - Frozen

Immunohistology - Paraffin

Western Blotting

Product Specific References

Source Reference

  1. Smith, M. and Koch, G. (1987) Differential expression of murine macrophage surface glycoprotein antigens in intracellular membranes.
    J Cell Sci. 87:113-9.

References for CD68 antibody

  1. Ramprasad, M.P. et al. (1996) Cell surface expression of mouse macrosialin and human CD68 and their role as macrophage receptors for oxidized low density lipoprotein.
    Proc Natl Acad Sci U S A. 93 (25): 14833-8.
  2. Rabinowitz, S.S. & Gordon, S. (1991) Macrosialin, a macrophage-restricted membrane sialoprotein differentially glycosylated in response to inflammatory stimuli.
    J Exp Med. 174 (4): 827-36.
  3. da Silva, R.P. & Gordon, S. (1999) Phagocytosis stimulates alternative glycosylation of macrosialin (mouse CD68), a macrophage-specific endosomal protein.
    Biochem J. 338 ( Pt 3): 687-94.
  4. Schleicher, U. et al. (2005) Minute numbers of contaminant CD8+ T cells or CD11b+CD11c+ NK cells are the source of IFN-{gamma} in IL-12/IL-18-stimulated mouse macrophage populations.
    Blood 105: 1319-1328.
  5. Choi, E.J. et al. (2014) Novel brain arteriovenous malformation mouse models for type 1 hereditary hemorrhagic telangiectasia.
    PLoS One. 9(2): e88511.
  6. Kassim, S. et al. (2010) Gene therapy in a humanized mouse model of familial hypercholesterolemia leads to marked regression of atherosclerosis.
    PloS ONE 5: e13424.
  7. Rahaman, S.O. et al. (2011) Vav family Rho guanine nucleotide exchange factors regulate CD36-mediated macrophage foam cell formation.
    J Biol Chem. 286: 7010-7.
  8. Frossard, J.L. et al. (2011) Role of CCL-2, CCR-2 and CCR-4 in cerulein-induced acute pancreatitis and pancreatitis-associated lung injury.
    J Clin Pathol. 64: 387-93
  9. West, E.L. et al. (2010) Long-term survival of photoreceptors transplanted into the adult murine neural retina requires immune modulation.
    Stem Cells. 28: 1997-2007.
  10. Lopez, M.E. et al. (2011) Anatomically defined neuron-based rescue of neurodegenerative niemann-pick type C disorder.
    J Neurosci. 31: 4367-78.
  11. Jayagopal, A. et al. (2009) Quantum dot mediated imaging of atherosclerosis.
    Nanotechnology. 20: 165102.
  12. Leung, V.W. et al. (2009) Decay-accelerating factor suppresses complement C3 activation and retards atherosclerosis in low-density lipoprotein receptor-deficient mice.
    Am J Pathol. 175: 1757-67.
  13. Devey, L. et al. (2009) Tissue-resident macrophages protect the liver from ischemia reperfusion injury via a heme oxygenase-1-dependent mechanism.
    Mol Ther. 17: 65-72.
  14. Lu, W. et al. (2010) Photoacoustic imaging of living mouse brain vasculature using hollow gold nanospheres.
    Biomaterials. 31: 2617-26.
  15. de Beer, M.C. et al. (2003) Lack of a direct role for macrosialin in oxidized LDL metabolism.
    J Lipid Res. 44: 674-85.
  16. Song, L. et al. (2011) Deletion of the murine scavenger receptor CD68.
    J Lipid Res. 52: 1542-50.
  17. Daldrup-Link, H.E. et al. (2011) MR Imaging of Tumor Associated Macrophages with Clinically-Applicable Iron Oxide Nanoparticles.
    Clin Cancer Res. 17: 5695-704.
  18. Macauley, S.L. et al. (2011) The Role of Attenuated Astrocyte Activation in Infantile Neuronal Ceroid Lipofuscinosis
    J. Neurosci 31: 15575-85.
  19. Martin-Manso, G. et al. (2008) Thrombospondin 1 promotes tumor macrophage recruitment and enhances tumor cell cytotoxicity of differentiated U937 cells.
    Cancer Res. 68: 7090-9.
  20. Lazarini, F. et al. (2012) Early Activation of Microglia Triggers Long-Lasting Impairment of Adult Neurogenesis in the Olfactory Bulb
    J Neurosci 32: 3652-64
  21. Hemmi, H. et al. (2009) A new triggering receptor expressed on myeloid cells (Trem) family member, Trem-like 4, binds to dead cells and is a DNAX activation protein 12-linked marker for subsets of mouse macrophages and dendritic cells.
    J Immunol. 182: 1278-86.
  22. Akbarshahi, H. et al. (2012) Enrichment of Murine CD68(+)CCR2(+) and CD68(+)CD206(+) Lung Macrophages in Acute Pancreatitis-Associated Acute Lung Injury.
    PLoS One. 7: e42654.
  23. Xiang, X. et al. (2016) TREM2 deficiency reduces the efficacy of immunotherapeutic amyloid clearance.
    EMBO Mol Med. 8 (9): 992-1004.
  24. Masaki, T. et al. (2003) Heterogeneity of antigen expression explains controversy over glomerular macrophage accumulation in mouse glomerulonephritis.
    Nephrol. Dial. Transplant 18:178-81.
  25. Dormishian, M. et al. (2013) Prokineticin receptor-1 is a new regulator of endothelial insulin uptake and capillary formation to control insulin sensitivity and cardiovascular and kidney functions.
    J Am Heart Assoc. 2 (5): e000411.
  26. von Bargen, K. et al. (2014) Cervical Lymph Nodes as a Selective Niche for Brucella during Oral Infections.
    PLoS One. 10 (4): e0121790.
  27. Hamour, S. et al. (2015) Local IL-17 Production Exerts a Protective Role in Murine Experimental Glomerulonephritis.
    PLoS One. 10 (8): e0136238.
  28. Wang L et al. (2016) Bone Fracture Pre-Ischemic Stroke Exacerbates Ischemic Cerebral Injury in Mice.
    PLoS One. 11 (4): e0153835.
  29. Nguyen, T.V. et al. (2016) Multiplex immunoassay characterization and species comparison of inflammation in acute and non-acute ischemic infarcts in human and mouse brain tissue.
    Acta Neuropathol Commun. 4 (1): 100.
  30. Pena-Philippides, J.C. et al. (2016) In vivo inhibition of miR-155 significantly alters post-stroke inflammatory response.
    J Neuroinflammation. 13 (1): 287.
  31. Paiva, A. A. et al. (2017) Apolipoprotein CIII Overexpression-Induced Hypertriglyceridemia Increases Nonalcoholic Fatty Liver Disease in Association with Inflammation and Cell Death.
    Oxidative Med Cellular Longev. 2017: 1-18.
  32. Giraldo, J.A. et al. (2016) The impact of cell surface PEGylation and short-course immunotherapy on islet graft survival in an allogeneic murine model.
    Acta Biomater. pii: S1742-7061(16)30656-0. [Epub ahead of print]
  33. Masuda, T. et al. (2017) Growth Factor Midkine Promotes Nuclear Factor of Activated T Cells-Regulated T-Cell-Activation and Th1 Cell Differentiation in Lupus Nephritis.
    Am J Pathol. Feb 6. pii: S0002-9440(17)30029-9. [Epub ahead of print]
  34. Garofalo, S. et al. (2017) The glycoside oleandrin reduces glioma growth with direct and indirect effects on tumor cells.
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  35. Maeda, K. et al. (2017) Inhibition of H3K9 methyltransferase G9a ameliorates methylglyoxal-induced peritoneal fibrosis.
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