MBP antibody | 26

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Mouse anti Human MBP (aa67-74)

Product Type
Monoclonal Antibody
Clone
26
Isotype
IgG1
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
MCA685S C 2 ml
Mouse anti MBP antibody, clone 26 recognizes an epitope between amino acids 67 and 74 of human myelin basic protein, also known as MBP, Myelin A1 protein or Myelin membrane encephalitogenic protein. MBP is a 304 amino acid ~33 kDa abundant component of the myelin membrane. There are 6 potential isoforms of MBP generated by alternative splicing, 4 of which lack the N-terminal region containing the immunogen sequence. Mouse anti MBP antibody, clone 26 is expected to recognize isoforms 1 and 2 (UniProt: P02686) . The N-terminal region of MBP is highly conserved and Mouse anti MBP antibody, clone 26 is expected to be broadly species cross reactive for isoforms maintaining the N-terminal region.

Product Details

Target Species
Human
Product Form
Tissue Culture Supernatant - liquid
Preparation
Tissue Culture Supernatant containing 0.1M Tris/HCl and foetal calf serum.
Preservative Stabilisers
0.09%Sodium Azide
Immunogen
Human myelin basic protein.
Fusion Partners
Spleen cells from immunized mice were fused with cells of the mouse SP2/0 myeloma cell line.

Storage Information

Storage
Store at +4oC or at -20oC if preferred.

This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life
18 months from date of despatch.

More Information

UniProt
P02686 Related reagents
Entrez Gene
MBP Related reagents
Regulatory
For research purposes only

Applications of MBP antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunohistology - Frozen
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.

Product Specific References

References for MBP antibody

  1. Groome, N. et al. (1988) New monoclonal antibodies reactive with defined sequential epitopes in human myelin basic protein.
    J Neuroimmunol. 19 (4): 305-15.
  2. Martenson, R.E. (1984) Experimental allergic encephalomyelitis. A useful model of multiple sclerosis
    Eds Alvord, Kies and Suckling pp 511-521. Alan Liss N.Y.