IgG1 antibody | 2C11
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Mouse anti Human IgG1
- Product Type
- Monoclonal Antibody
- Clone
- 2C11
- Isotype
- IgG1
- Specificity
- IgG1
Antibody Quality and Performance Guarantee
| Mouse anti Human IgG1 antibody, clone 2C11 reacts with the γ2-specific epitope inside the Fc fragment of human IgG1. It does not cross react with other human immunoglobulins. |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- <0.1% Sodium Azide (NaN3)
- Immunogen
- Purified human IgG.
- Approx. Protein Concentrations
- IgG concentration 0.5 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |  |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.
References for IgG1 antibody
-
Stubbs, J. et al. (2011) Strain-transcending Fc-dependent killing of Plasmodium falciparum by merozoite surface protein 2 allele-specific human antibodies.
Infect Immun. 79 (3): 1143-52. -
Caturegli, P. et al. (2016) Hypophysitis Secondary to Cytotoxic T-Lymphocyte-Associated Protein 4 Blockade: Insights into Pathogenesis from an Autopsy Series.
Am J Pathol. 186 (12): 3225-35. -
Wallukat, G. et al. (2017) Autoantibodies Directed Against the Endothelin A Receptor in Patients With Benign Prostatic Hyperplasia.
Prostate. 77 (5): 458-65. -
Martinsson, K. et al. (2017) Immunoglobulin (Ig)G1 and IgG4 anti-cyclic citrullinated peptide (CCP) associate with shared epitope, whereas IgG2 anti-CCP associates with smoking in patients with recent-onset rheumatoid arthritis (the Swedish TIRA project).
Clin Exp Immunol. 188 (1): 53-62.
- RRID
- AB_2126756
- UniProt
- P01857
- Entrez Gene
- IGHG1
- GO Terms
- GO:0005515 protein binding
- GO:0003823 antigen binding
- GO:0005576 extracellular region
- GO:0005624 membrane fraction
- GO:0006955 immune response
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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