CD95 antibody | E06-1A9
Mouse anti Human CD95
- Product Type
- Monoclonal Antibody
- Clone
- E06-1A9
- Isotype
- IgG1
- Specificity
- CD95
| Mouse anti Human CD95 antibody, clone E06-1A9, recognizes CD95, also known as TNFRSF6, Apo-1 antigen, apoptosis-mediating surface antigen FAS and FASLG receptor. It is a member of the TNF receptor superfamily and is a death receptor. CD95 is a type I transmembrane glycoprotein which is ubiquitously expressed, but it is particularly abundant in the thymus, liver, heart and kidney tissues (Peter et al. 2015). Upon binding of its ligand CD95L, CD95 interacts with adaptor proteins to form a death-inducing signaling complex to trigger a cell death signal. However CD95 is also able to promote inflammation, normal and tumor cell growth and migration through other signaling pathways including PI3K, NFκB and JNK MAPKs (Levoin et al. 2020). The purified Mouse anti Human CD95 antibody, clone E06-1A9 (MCA62672GA) can be used as a capture antibody in a sandwich ELISA with the biotinylated Mouse anti Human CD95 antibody, clone C02-6C8 (MCA6273B) as the detection antibody. |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Carrier Free
- Yes
- Immunogen
- E. coli derived recombinant human full length CD95 (Gln26-Val335)
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Fusion Partners
- Cell fusion between immunized BALB/c mouse spleen cells and mouse myeloma SP2/0
- ELISA Matched Pair(s)
-
ELISA Matched Pair-Detection Antibody:
MCA6273B
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |  |
1.0 ug/ml |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Mouse anti Human CD95:Biotin | MCA6273B | E | 0.1 mg |
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| List Price | Your Price | ||||||
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| Description | Mouse anti Human CD95:Biotin | ||||||
MCA6272GA
100005435
If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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