CD44v7/8 antibody | VFF-17
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Mouse anti Human CD44v7/8
- Product Type
- Monoclonal Antibody
- Clone
- VFF-17
- Isotype
- IgG2b
- Specificity
- CD44v7/8
Antibody Quality and Performance Guarantee
| Mouse anti Human CD44v7/8 antibody, clone VFF-17 recognizes an epitope encoded by exons v7-v8 on the variant portion of human CD44. |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Antibody purified from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- None present
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- Guaranteed until date of expiry. Please see product label.
Store at -20°C only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Flow Cytometry |  |
1/10 | 1/100 |
| Immunohistology - Frozen | |
1/100 | 1/1000 |
| Immunohistology - Paraffin 1 | |
1/100 |
- 1This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.Sodium citrate buffer pH 6.0 is recommended for this purpose.
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Flow Cytometry
- Use 10μl of the suggested working dilution to label 106 cells in 100μl
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Mouse IgG2b Negative Control | MCA691 | F | 100 Tests |
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| List Price | Your Price | ||||||
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| Description | Mouse IgG2b Negative Control | ||||||
References for CD44v7/8 antibody
-
Wibulswas, A. et al. (2000) The CD44v7/8 epitope as a target to restrain proliferation of fibroblast-like synoviocytes in rheumatoid arthritis.
Am J Pathol. 157 (6): 2037-44. -
Alam, T.N. et al. (2004) Differential expression of CD44 during human prostate epithelial cell differentiation.
J Histochem Cytochem. 52: 1083-90. -
Hanley, W.D. et al. (2006) Variant isoforms of CD44 are P- and L-selectin ligands on colon carcinoma cells.
FASEB J. 20: 337-9. -
Rajarajan, A. et al. (2012) CD44 expression in oro-pharyngeal carcinoma tissues and cell lines.
PLoS One. 7: e28776. -
Bauer, S. et al. (2006) Fibroblast activation protein is expressed by rheumatoid myofibroblast-like synoviocytes.
Arthritis Res Ther. 8: R171. -
Shirure, V.S. et al. (2015) CD44 variant isoforms expressed by breast cancer cells are functional E-selectin ligands under flow conditions.
Am J Physiol Cell Physiol. 308 (1): C68-78. -
Noori, M.S. et al. (2018) An adhesion based approach for the detection of esophageal cancer.
Integr Biol (Camb). 10 (12): 747-57.
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