Alpha Fetoprotein antibody | 2I9/2 (166)
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|Mouse anti Human alpha fetoprotein antibody, clone 219/2 recognizes alpha fetoprotein (AFP), a member of the albuminoid superfamily. It is a ~68 kDa plasma protein found in fetuses over four weeks old, produced by the yolk sac and the fetal liver, with the highest concentration reached during the 12th to 16th week of gestation. It binds and transports various ligands such as bilirubin, fatty acids, steroids, heavy metals and various drugs. After birth, plasma levels drop to trace amounts in healthy adults
Elevated AFP levels are indicative of certain cancers, particularly hepatocellular carcinoma, cancer of the testes or ovaries or a malignant teratoma. During pregnancy increased levels of AFP may indicate neural tube defects such as spina bifida, while decreased levels could indicate Down's syndrome.
Mouse anti Human alpha fetoprotein antibody, clone 219/2 does not cross-react with human albumin and other human serum proteins.
- Target Species
- Product Form
- Ig fraction - liquid
- Ig fraction prepared by chromatography from ascites
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- <0.1% Sodium Azide (NaN3)
- Human fetal cord serum.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- For research purposes only
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
|Application Name||Verified||Min Dilution||Max Dilution|
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"View all Anti-Human Products
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