Lymphocytes antibody | MsGp2
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|Mouse anti Guinea Pig lymphocytes and Langerhans cells antibody, clone MsGp2 recognizes an antigen present on the majority of T and B lymphocytes and thymocytes, although the antigen is not expressed by germinal centre cells of the lymph node (Kraal et al. 1986).
Mouse anti Guinea Pig lymphocytes and Langerhans cells antibody, clone MsGp2 also reacts strongly with epidermal Langerhans cells, giving a superior profile than anti-MHC Class II antibodies on these cells (Healey et al. 1987). Clone MsGp2 does not functionally inhibit lymphocyte adherence to high endothelial venules in vitro (Healey et al. 1987).
- Target Species
- Guinea Pig
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Carrier Free
- Nylon wool adherent B cells
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Fusion Partners
- Spleen cells from immunized BALB/c mice were fused with cells from the NS1 mouse myeloma cell line
- For research purposes only
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
|Application Name||Verified||Min Dilution||Max Dilution|
|Immunohistology - Frozen|
References for Lymphocytes antibody
Healey, D.G. et al. (1987) An antigenic determinant common to lymphocytes and Langerhans cells of the guinea pig.
Int Arch Allergy Appl Immunol. 82 (2): 120-4.
Kraal, G. et al. (1986) A surface molecule on guinea pig lymphocytes involved in adhesion and homing.
Eur J Immunol. 16 (12): 1515-9.
Baker, D. et al. (1987) Induction of sensitization and tolerance in contact sensitivity with haptenated epidermal cells in the guinea-pig.
Immunology. 62 (4): 659-64.
Mendoza, J.M. et al. (2013) Elucidating the Kinetics of Expression and Immune Cell Infiltration Resulting from Plasmid Gene Delivery Enhanced by Surface Dermal Electroporation.
Vaccines (Basel). 1 (3): 384-97.
Smith, T.R. et al. (2014) DNA vaccination strategy targets epidermal dendritic cells, initiating their migration and induction of a host immune response.
Mol Ther Methods Clin Dev. 1: 14054.
Sato H & Kamiya H (1995) Role of epidermal Langerhans' cells in the induction of protective immunity to Schistosoma mansoni in guinea-pigs.
Immunology. 84 (2): 233-40.
Schäfer, H. et al. (1991) T cell proliferation induced by monoclonal antibodies to a phosphatidylinositol-linked differentiation antigen of guinea pig lymphocytes.
Eur J Immunol. 21 (3): 701-5.
Schäfer, H. & Burger, R. (2012) Tools for cellular immunology and vaccine research the in the guinea pig: monoclonal antibodies to cell surface antigens and cell lines.
Vaccine. 30 (40): 5804-11.
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