Mouse anti PI-3 Kinase p85 Subunit beta antibody, clone T15 recognizes the p85 subunit of bovine PI-3 kinase.
- Target Species
- Species Cross-Reactivity
|Target Species||Cross Reactivity|
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- Carrier Free
- Balculovirus expressed (Recombinant) p85 beta subunit of bovine PI-3 kinase.
- Approx. Protein Concentrations
- 1.0 mg/ml
- Fusion Partners
- Spleen cells from immunized mice were fused with cells of the NS1 mouse myeloma cell line.
- Store at +4oC or at -20oC if preferred
This product should be stored undiluted
Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
GTPase activator activity
phosphatidylinositol 3-kinase complex
small GTPase mediated signal transduction
insulin receptor signaling pathway
fibroblast growth factor receptor signaling pathway
negative regulation of anti-apoptosis
T cell costimulation
phosphatidylinositol 3-kinase regulator activity
nerve growth factor receptor signaling pathway
T cell receptor signaling pathway
regulation of small GTPase mediated signal transduction
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of PI-3 Kinase p85 Subunit Beta antibody
|Immunohistology - Frozen
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
Copyright © 2020 Bio-Rad Antibodies (formerly AbD Serotec)
Secondary Antibodies Available
Application Based External Images
Product Specific References
References for PI-3 Kinase p85 Subunit Beta antibody
Brehme,M. et al (2009) Charting the molecular network of the drug target Bcr-Abl.
Proc Natl Acad Sci U S A,. 106: 7414-9
Hale, B.G. et al. (2008) Binding of influenza A virus NS1 protein to the inter-SH2 domain of p85 suggests a novel mechanism for phosphoinositide 3-kinase activation.
J Biol Chem. 283: 1372-80.
Ehrhardt, C. et al. (2007) Influenza A virus NS1 protein activates the PI3K/Akt pathway to mediate antiapoptotic signaling responses.
J Virol. 81: 3058-67.
Massone, C. et al. (2011) Immunophenotype of skin lymphocytic infiltrate in patients co-infected with Mycobacterium leprae and human immunodeficiency virus: a scenario dependent on CD8+ and/or CD20+ cells.
Br J Dermatol. 165: 321-8.
Yokoyama, K. et al. (2011) NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons.
EMBO J. 30: 4739-54.
Ylösmäki, L. et al. (2015) Reorganization of the host cell Crk(L)-PI3 kinase signaling complex by the influenza A virus NS1 protein.
Virology. 484: 146-52.