Kinesin Heavy Chain antibody | H2
Kinesins are microtubule associated motor proteins, responsible for converting nucleoside triphosphate released energy into mechanical energy. Kinesin-1 exists as a homodimer of 120-130 kDa chains, known as heavy chains. Associated with this dimer when purified from brain homogenates are light chains of 60-70 kDa. The light chains are involved in binding of kinesin to organelles and appear to have regulatory functions. They are not essential for motility generation.
- Target Species
- Species Cross-Reactivity
Target Species Cross Reactivity Mammals Expected from Sequence Chicken Expected from Sequence Invertebrates Expected from Sequence
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.1% Sodium Azide (NaN3)
- Bovine brain kinesin.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
- 12 months from date of despatch
- For research purposes only
Applications of Kinesin Heavy Chain antibody
|Application Name||Verified||Min Dilution||Max Dilution|
|Immunohistology - Frozen|
|Immunohistology - Paraffin|
Secondary Antibodies Available
Product Specific References
References for Kinesin Heavy Chain antibody
Pfister, K.K. et al. (1989) Monoclonal antibodies to kinesin heavy and light chains stain vesicle-like structures, but not microtubules, in cultured cells.
J Cell Biol. 108 (4): 1453-63.
Kamm, C. et al. (2004) The early onset dystonia protein torsinA interacts with kinesin light chain 1.
J Biol Chem. 279 (19): 19882-92.
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