Newcastle Disease Virus antibody | 9F7
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Mouse anti Newcastle Disease Virus antibody, clone 9F7 detects the La-Sota strain of the Newcastle Disease Virus (NDV), a highly contagious avian virus which is of major economic importance to the poultry industry. NDV is a member of the Paramyxoviridae family, and has a single stranded, negative sense RNA genome.
NDV infects via mucosal surfaces of the respiratory and alimentary tract, and its strains can be categorized in accordance to their virulence, from low virulence and mild symptoms (lentogenic), to intermediate forms (mesogenic), through to highly virulent (velogenic) strains which can cause up to 90% mortality. La-Sota is a lentogenic strain, and can be used as a live vaccine.
NDV has been reported to selectively kill human tumour cells in a number of clinical studies.
NDV infects via mucosal surfaces of the respiratory and alimentary tract, and its strains can be categorized in accordance to their virulence, from low virulence and mild symptoms (lentogenic), to intermediate forms (mesogenic), through to highly virulent (velogenic) strains which can cause up to 90% mortality. La-Sota is a lentogenic strain, and can be used as a live vaccine.
NDV has been reported to selectively kill human tumour cells in a number of clinical studies.
Product Details
- Target Species
- Viral
- Product Form
- Purified IgG- liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.09% Sodium Azide (NaN3) - Immunogen
- Glycoprotein haemagglutinin-neuraminidase of Newcastle Disease Virus (La-Sota strain).
- Approx. Protein Concentrations
- IgG concentration 1.0mg/ml
- Fusion Partners
- Spleen cells from immunised Balb/c mice were fused with cells of the Sp2/0 myeloma cell line.
Storage Information
- Storage
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. - Shelf Life
- 18 months from date of despatch.
More Information
- Regulatory
- For research purposes only
Applications of Newcastle Disease Virus antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Copyright © 2019 Bio-Rad Antibodies (formerly AbD Serotec)
Secondary Antibodies Available
Product Specific References
References for Newcastle Disease Virus antibody
-
Lorence, R.M. et al. (2007) Phase 1 clinical experience using intravenous administration of PV701, an oncolytic Newcastle disease virus.
Curr Cancer Drug Targets. 7 (2): 157-67. -
Huang, Z. et al. (2003) Recombinant Newcastle disease virus as a vaccine vector.
Poult Sci. 82 (6): 899-906.
