Influenza B Nucleoprotein antibody | B017 (B35G)
The influenza viruses, classified as type A, B and C, are members of the Orthomyxoviridae family which differ in their epidemiology and host ranges and lack serological cross-reactivity of their internal components, especially their matrix proteins and nucleoprotein. Influenza B virus is a slow-mutating single stranded RNA virus subject to antigenic drift which, although enough to prevent lasting immunity, prevents influenza B from causing pandemics.
Mouse anti Influenza B Nucleoprotein antibody, clone B017 can be used in influenza B IFA typing in conjunction with MCA2717 (clone B114).
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography from tissue culture supernatant.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.09% Sodium Azide
- Influenza B/Lee/40 and B/Singapore/-222/79 viruses.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Fusion Partners
- Spleen cells from immunised BALB/c mice were fused with cells of the P3 Ag8.653 mouse myeloma cell line.
- Store at +4oC or at -20oC if preferred.
This product should be stored undiluted.
Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- For research purposes only
Applications of Influenza B Nucleoprotein antibody
|Application Name||Verified||Min Dilution||Max Dilution|
Secondary Antibodies Available
Product Specific References
References for Influenza B Nucleoprotein antibody
Walls, H.H. et al. (1986) Characterization and evaluation of monoclonal antibodies developed for typing influenza A and influenza B viruses.
J Clin Microbiol. 23 (2): 240-5.
Zhirnov, O.P. et al. (1999) Caspase-dependent N-terminal cleavage of influenza virus nucleocapsid protein in infected cells.
J Virol. 73 (12): 10158-63.
Ehrhardt, C. et al. (2007) Activation of phosphatidylinositol 3-kinase signaling by the nonstructural NS1 protein is not conserved among type A and B influenza viruses.
J Virol. 81 (21): 12097-100.
Goujon, C. & Malim, M.H. (2010) Characterization of the alpha interferon-induced postentry block to HIV-1 infection in primary human macrophages and T cells.
J Virol. 84 (18): 9254-66.
Dauber, B. et al. (2009) Influenza B virus ribonucleoprotein is a potent activator of the antiviral kinase PKR.
PLoS Pathog. 5 (6): e1000473.
How to Use the Spectraviewer?
- Start by selecting the application you are interested in, with the option to select an instrument from the drop down menu or create a customized instrument
- Select the fluorophores or fluorescent proteins you want to include in your panel to check compatibility
- Select the lasers and filters you wish to include
- Select combined or multi-laser view to visualize the spectra