Influenza B Nucleoprotein antibody | B017 (B35G)
The influenza viruses, classified as type A, B and C, are members of the Orthomyxoviridae family which differ in their epidemiology and host ranges and lack serological cross-reactivity of their internal components, especially their matrix proteins and nucleoprotein. Influenza B virus is a slow-mutating single stranded RNA virus subject to antigenic drift which, although enough to prevent lasting immunity, prevents influenza B from causing pandemics.
Mouse anti Influenza B Nucleoprotein antibody, clone B017 can be used in influenza B IFA typing in conjunction with MCA2717 (clone B114).
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography from tissue culture supernatant.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- <0.1% Sodium Azide (NaN3)
- Influenza B/Lee/40 and B/Singapore/-222/79 viruses.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Fusion Partners
- Spleen cells from immunised BALB/c mice were fused with cells of the P3 Ag8.653 mouse myeloma cell line.
- This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
- 12 months from date of despatch
- For research purposes only
Applications of Influenza B Nucleoprotein antibody
|Application Name||Verified||Min Dilution||Max Dilution|
Secondary Antibodies Available
Product Specific References
References for Influenza B Nucleoprotein antibody
Walls, H.H. et al. (1986) Characterization and evaluation of monoclonal antibodies developed for typing influenza A and influenza B viruses.
J Clin Microbiol. 23 (2): 240-5.
Zhirnov, O.P. et al. (1999) Caspase-dependent N-terminal cleavage of influenza virus nucleocapsid protein in infected cells.
J Virol. 73 (12): 10158-63.
Ehrhardt, C. et al. (2007) Activation of phosphatidylinositol 3-kinase signaling by the nonstructural NS1 protein is not conserved among type A and B influenza viruses.
J Virol. 81 (21): 12097-100.
Goujon, C. & Malim, M.H. (2010) Characterization of the alpha interferon-induced postentry block to HIV-1 infection in primary human macrophages and T cells.
J Virol. 84 (18): 9254-66.
Dauber, B. et al. (2009) Influenza B virus ribonucleoprotein is a potent activator of the antiviral kinase PKR.
PLoS Pathog. 5 (6): e1000473.
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