Mouse anti Hepatitis C E2 antigen antibody, clone 1876
recognizes the envelope glycoprotein E2 of Hepatitis C virus (HCV). It has been suggested that HCV infects human cells through interaction of the E2 envelope glycoprotein and CD81 the putative viral receptor (Fénéant et al. 2014
- Target Species
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antisera to Hepatitis C virus envelope glycoprotein E2 were raised by repeated immunisations of mice with highly purified antigen. Purified IgG was prepared from ascites or tissue culture medium by protein A affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- Approx. Protein Concentrations
- IgG concentration 0.1mg/ml
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted.
Avoid repeated freezing and thawing as this may denature the antibody.
- 12 months from date of reconstitution.
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of Hepatitis C E2 Antigen antibody
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
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Secondary Antibodies Available
Product Specific References
Machida, K. et al. (2005) Hepatitis C virus E2-CD81 interaction induces hypermutation of the immunoglobulin gene in B cells.
J Virol. 79 (13): 8079-89.