IL-1 Beta antibody | DF8
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Mouse anti Pig Interleukin-1 beta:Preservative Free
- Product Type
- Monoclonal Antibody
- Clone
- DF8
- Isotype
- IgG1
- Specificity
- IL-1 Beta
Antibody Quality and Performance Guarantee
| Mouse anti Porcine interleukin-1 beta antibody, clone DF8 recognizes porcine interleukin-1 beta (IL-1 beta). IL-1 beta is principally expressed by macrophages, and plays an important immunomodulatory role in the porcine immune response. |
- Target Species
- Pig
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- None present
- Immunogen
- Recombinant porcine IL-1 beta.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Endotoxin Level
- < 0.015 EU/μg
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Store at -20°C.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting |  |
1ug/ml | 5ug/ml |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
References for IL-1 Beta antibody
-
Zelnickova, P. et al. (2008) Age-dependent changes of proinflammatory cytokine production by porcine peripheral blood phagocytes.
Vet Immunol Immunopathol. 124: 367-78. -
Shao, Y. et al. (2016) HMGB1/TLR4 signaling induces an inflammatory response following high-pressure renal pelvic perfusion in a porcine model.
Am J Physiol Renal Physiol. : ajprenal.00480.2015.
- RRID
- AB_567066
- UniProt
- P26889
- Entrez Gene
- IL1B
- GO Terms
- GO:0001660 fever generation
- GO:0005125 cytokine activity
- GO:0005149 interleukin-1 receptor binding
- GO:0005615 extracellular space
- GO:0006955 immune response
- GO:0008083 growth factor activity
- GO:0051781 positive regulation of cell division
MCA2361Z
161007
If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
View more products with IL-1 BETA specificity
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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