YKL-40 antibody | G06-10H11
Mouse anti Human YKL-40
- Product Type
- Monoclonal Antibody
- Clone
- G06-10H11
- Isotype
- IgG1
- Specificity
- YKL-40
Antibody Quality and Performance Guarantee
| Mouse anti Human YKL-40 antibody, clone G06-10H11, recognizes YKL-40, also known as chitinase-3-like protein 1, 39kDA synovial protein and cartilage glycoprotein 39. YKL-40 is a glycoprotein and a member of the mammalian chitinase-like proteins (Johansen et al. 2006). It is expressed by a variety of cells including macrophages, neutrophils, chondrocytes, fibroblasts, vascular smooth muscle cells, endothelial cells and epithelials cells (Lee et al. 2011). YKL-40 induces the maturation of monocytes to macrophages and is secreted by macrophages during late stages of differentiation and by activated macrophages. It has also been shown to be an adhesion and migration factor for vascular cells (Rathcke & Vestergaard 2009). The purified Mouse anti Human YKL-40 antibody, clone G06-10H11 (MCA6290GA) can be used as a capture antibody in a sandwich ELISA with the biotinylated Mouse anti Human YKL-40 antibody, clone G03-2H1 (MCA6291B) as the detection antibody. |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Carrier Free
- Yes
- Immunogen
- NS0 derived recombinant full length human YKL-40 (Tyr22-Thr383)
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Fusion Partners
- Cell fusion between immunized BALB/c mouse spleen cells and mouse myeloma SP2/0
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |  |
1.0 ug/ml |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Mouse anti Human YKL-40:Biotin | MCA6291B | E | 0.1 mg |
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| Description | Mouse anti Human YKL-40:Biotin | ||||||
- Synonyms
- Chitinase-3-like Protein 1
- UniProt
- P36222
- Entrez Gene
- CHI3L1
- GO Terms
- GO:0004568 chitinase activity
- GO:0005201 extracellular matrix structural constituent
- GO:0005529 sugar binding
- GO:0005578 proteinaceous extracellular matrix
- GO:0005615 extracellular space
- GO:0006032 chitin catabolic process
- GO:0043169 cation binding
MCA6290GA
100005243
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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