Transferrin antibody | HTF-14
Transferrin is a 77 kDa plasma protein synthesized by the liver involved with the transport of iron. Each transferrin molecule has two domains, both with facility to carry 2 ferric ions. The iron/transferrin complex is essential for hemoglobin synthesis and certain types of cell division.
- Target Species
- Species Cross-Reactivity
Target Species Cross Reactivity Sheep Pig Bovine Dog Horse Rabbit Rat
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein A
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.09% Sodium Azide (NaN3)
- Purified porcine transferrin.
- Approx. Protein Concentrations
- IgG concentration 1mg/ml
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted.
Avoid repeated freezing and thawing as this may denature the antibody.
Should this product contain a precipitate we recommend microcentrifugation before use.
- 18 months from date of despatch.
- P02787 Related reagents
- Entrez Gene
- TF Related reagents
- GO Terms
- GO:0002576 platelet degranulation
- GO:0005576 extracellular region
- GO:0005769 early endosome
- GO:0005770 late endosome
- GO:0030141 stored secretory granule
- GO:0030139 endocytic vesicle
- GO:0005905 coated pit
- GO:0006879 cellular iron ion homeostasis
- GO:0008199 ferric iron binding
- GO:0009925 basal plasma membrane
- GO:0010008 endosome membrane
- GO:0016324 apical plasma membrane
- GO:0030168 platelet activation
- GO:0033572 transferrin transport
- GO:0048471 perinuclear region of cytoplasm
- GO:0055037 recycling endosome
- GO:0055085 transmembrane transport
- For research purposes only
Applications of Transferrin antibody
|Application Name||Verified||Min Dilution||Max Dilution|
- Western Blotting
- HTF-14 recognises a band of approximately 77kDa under reducing conditions in human plasma.
Secondary Antibodies Available
Product Specific References
References for Transferrin antibody
Rubikaite, B.I. et al. (1989) [Identification of the segment for binding of transferrin using a cellular receptor].
Mol Biol (Mosk). 23: 765-71.
Hradilek, A. and Neuwirt, J. (1986) Iron uptake by MOLT 3 cells from transferrin/monoclonal antitransferrin antibody complexes.
Br J Haematol. 62: 21-30.
Trebichavsky, I. et al. (1987) Monoclonal antibodies against pig transferrin. Blocking and binding activity.
Folia Microbiol (Praha). 32: 448-52.
Fuchs, O. et al. (1988) Non-transferrin donors of iron for heme synthesis in immature erythroid cells.
Biochim Biophys Acta. 969: 158-65.
Bártek, J. et al. (1985) Phylogenetically more conservative epitopes among monoclonal antibody-defined antigenic sites of human transferrin are involved in receptor binding.
Br J Haematol. 59: 435-41.
Penhallow, R.C. et al. (1986) Comparative studies of the binding and growth-supportive ability of mammalian transferrins in human cells.
J Cell Physiol. 128: 251-60.
Funk, W.D. et al. (1990) Expression of the Amino-Terminal Half-Molecule of Human Serum Transferrin in Cultured Cells and Characterization of the Recombinant Protei
Biochemistry. 29: 1654-60.