SOX9 antibody | 3C10
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|Mouse anti Human SOX9 antibody, clone 3C10 recognizes human Transcription factor SOX-9, also known SOX9, a 509 amino acid ~56 kDa transcription factor.
Mutation of the SOX9 gene can lead to development of Campomelic dysplasia (CMD1) an osteochondrodysplasia with bowing and angulation of the long bones along with other skeletal malformations (Kwok et al. 1995). Mutation can also lead to 46,XX sex reversal 2 (SRXX2) presenting with male gonads in a genetic female (Cox et al. 2011) or 46,XY sex reversal 10 (SRXY10) with gonadal dysgensis (Kim et al. 2015).
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein A
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- None present
- Recombinant protein corresponding to aa 400-510 of human SOX9
- Approx. Protein Concentrations
- Ig concentration 0.5 mg/ml
- Fusion Partners
- Spleen cells from BALB/c mice were fused with cells from the Sp2/0 myeloma cell line.
- For research purposes only
- 12 months from date of despatch
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
|Application Name||Verified||Min Dilution||Max Dilution|
|Immunohistology - Paraffin||0.1||10 ug/ml|
|Western Blotting||0.1||10 ug/ml|
References for SOX9 antibody
Menzel-severing, J. et al. (2018) Transcription factor profiling identifies Sox9 as regulator of proliferation and differentiation in corneal epithelial stem/progenitor cells.
Sci Rep. 8 (1): 10268.
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