Osteocalcin antibody | 2D4
Mouse anti Human Osteocalcin:Preservative Free
- Product Type
- Monoclonal Antibody
- Clone
- 2D4
- Isotype
- IgG1
- Specificity
- Osteocalcin
Mouse anti Human osteocalcin antibody, clone 2D4 recognizes human osteocalcin, also known as bone gla protein or Gamma-carboxyglutamic acid-containing protein. Osteocalcin is a 49 amino acid ~5 kDa calcium-binding bone protein comprising ~1-2% total bone protein mass. Osteocalcin also has an additional 28 amino acid propeptide region along with a 23 amino acid signal peptide region. |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein A from ascites
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- None present
- Immunogen
- Recombinant protein corresponding to aa 52-100 of human osteocalcin.
- Approx. Protein Concentrations
- Ig concentration 0.5 mg/ml
- Fusion Partners
- Spleen cells from BALB/c mice were fused with cells from the Sp2/0 myeloma cell line.
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Immunofluorescence | 0.1 | 10 ug/ml |
References for Osteocalcin antibody
-
Kover, K. et al. (2011) Bone marrow cavity: a supportive environment for islet engraftment.
Islets. 3: 93-101. -
Oliveira, M.B. et al. (2016) Autonomous osteogenic differentiation of hASCs encapsulated in methacrylated gellan-gum hydrogels.
Acta Biomater. 41: 119-32. -
Mizoshiri, N. et al. (2015) Transduction of Oct6 or Oct9 gene concomitant with Myc family gene induced osteoblast-like phenotypic conversion in normal human fibroblasts.
Biochem Biophys Res Commun. 467 (4): 1110-6.
- Synonyms
- Bone GLA Protein
- RRID
- AB_2065035
- UniProt
- P02818
- Entrez Gene
- BGLAP
- GO Terms
- GO:0005509 calcium ion binding
- GO:0007155 cell adhesion
- GO:0008147 structural constituent of bone
- GO:0030282 bone mineralization
- GO:0030500 regulation of bone mineralization
- GO:0042476 odontogenesis
- GO:0045124 regulation of bone resorption
- GO:0045670 regulation of osteoclast differentiation
- GO:0046848 hydroxyapatite binding
- View More GO Terms
MCA5225Z
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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