NCOA1 antibody | C02/13A7
Mouse anti Human NCOA1
- Product Type
- Monoclonal Antibody
- Clone
- C02/13A7
- Isotype
- IgG1
- Specificity
- NCOA1
Antibody Quality and Performance Guarantee
| Mouse anti human NCOA1 antibody, clone C02/13A7 recognizes Nuclear receptor coactivator 1 protein, also known as NCoA-1. NCOA1 is part of the p160 steroid receptor coactivator (SRC) family, and plays a crucial role in gene regulation. Dysregulation of NCOA1 results in progression and initiation of different cancers (Wang et al. 2018). Coactivators such as NCOA1 interact with sex steroid receptors such as estrogen receptor (ER) and androgen receptor (AR). Due to this interaction, there has been a great interest in study of breast and prostate cancers, and has generally been seen to be high in these cancers (Kazan and Gunduz et al. 2018). |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Immunogen
- E. coli-derived recombinant protein, aa 1-470 of human NCOA1.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting |  |
1/2,000 |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Western Blotting
- Mouse anti human NCOA1 detects a band of approximately 185 kDa in HEK293 cell lysates.
MCA6431GA
100007871
If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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