MTMR2 antibody | 4G6
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WB ResetMouse anti Human MTMR2:Preservative Free
- Product Type
- Monoclonal Antibody
- Clone
- 4G6
- Isotype
- IgG2a
- Specificity
- MTMR2
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Antibody Quality and 
Unrivaled 
| Mouse anti Human MTMR2 antibody, clone 4G6 recognizes human Myotubularin-related protein 2, also known as MTMR2, Phosphatidylinositol-3,5-bisphosphate 3-phosphatase or Phosphatidylinositol-3-phosphate phosphatase. MTMR2 is a 643 amino acid ~75 kDa phosphatase. Mutations in the MTMR2 gene can lead to development of Charcot-Marie-Tooth disease 4B1 (CMT4B1), an autosomal recessive demyelinating disease marked by progressive atrophy and weakness of peroneal and arm muscles (Bolino et al. 2000). |
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Rat - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein A
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- None present
- Immunogen
- Recombinant protein corresponding to aa 5-101 of human MTMR2
- Approx. Protein Concentrations
- Ig concentration 0.5 mg/ml
- Fusion Partners
- Spleen cells from immunized Balb/c mice were fused with cells from the Sp2/0 myeloma cell line.
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Store at -20oC only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting |  |
0.1 | 10 ug/ml |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- RRID
- AB_2147837
- UniProt
- Q13614
- Entrez Gene
- MTMR2
- GO Terms
- GO:0004437 inositol or phosphatidylinositol phosphatase activity
- GO:0004725 protein tyrosine phosphatase activity
- GO:0005634 nucleus
- GO:0006470 protein dephosphorylation
- GO:0008138 protein tyrosine/serine/threonine phosphatase activity
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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