IL-3 antibody | 5A4-1-16
Upon binding to its receptor IL3-Rα, the JAK and STAT signaling pathways can be activated. This is used to activate plasmacytoid dendritic cells during viral infection and the expansion of mast cells and basophils during parasitic infection (Dougan et al. 2019).
Product Details
- Target Species
- Human
- Product Form
- Purified IgG - lyophilized
- Reconstitution
- Reconstitute with 0.5 ml distilled water
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- None present
- Carrier Free
- Yes
- Immunogen
- E. coli derived recombinant human interleukin-3
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml after reconstitution
- Endotoxin Level
- < 1 EU/μg
Storage Information
- Storage
- Prior to reconstitution store at -20°C.
After reconstitution store at -20°C.
This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. - Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P08700
- Entrez Gene
- IL3
- GO Terms
- GO:0005125 cytokine activity
- GO:0005135 interleukin-3 receptor binding
- GO:0005615 extracellular space
- GO:0006955 immune response
- GO:0007267 cell-cell signaling
- GO:0007399 nervous system development
- GO:0008083 growth factor activity
- GO:0008284 positive regulation of cell proliferation
- GO:0042523 positive regulation of tyrosine phosphorylation of Stat5 protein
- GO:0045740 positive regulation of DNA replication
- GO:0045885 positive regulation of survival gene product expression
- Regulatory
- For research purposes only
Applications of IL-3 antibody
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
ELISA | 8.0 ug/ml | 4.0 ug/ml | |
Western Blotting | 0.25 ug/ml | 0.5 ug/ml |
Secondary Antibodies Available
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