HLA DP DQ DR antibody | Bu26
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Mouse anti Human HLA DP DQ DR
- Product Type
- Monoclonal Antibody
- Clone
- Bu26
- Isotype
- IgG1
- Specificity
- HLA DP DQ DR
Antibody Quality and Performance Guarantee
| Mouse anti Human HLA DP DQ DR antibody, clone Bu26 reacts with DP, DQ and DR beta chains, which are expressed by antigen presenting cells, B cells, monocytes and activated T lymphocytes. The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In humans, this complex is referred to as the human leukocyte antigen (HLA) region. There are 3 major MHC class II proteins encoded by the HLA which are HLA DP, HLA DQ and HLA DR. |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.09% Sodium Azide (NaN3) - Carrier Free
- Yes
- Approx. Protein Concentrations
- IgG concentration 1.0mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Flow Cytometry |  |
1/100 | 1/200 |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Flow Cytometry
- Use 10ul of the suggested working dilution to label 1x106 cells in 100ul.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Mouse IgG1 Negative Control | MCA928 | F | 100 Tests |
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| List Price | Your Price | ||||||
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| Description | Mouse IgG1 Negative Control | ||||||
References for HLA DP DQ DR antibody
-
Chapple, M.R. et al. (1990) A phenotypic study of B lymphocyte subpopulations in human bone marrow.
Clin Exp Immunol. 81 (1): 166-72. -
Kumararatne, D.S. et al. (1990) Specific lysis of mycobacterial antigen-bearing macrophages by class II MHC-restricted polyclonal T cell lines in healthy donors or patients with tuberculosis.
Clin Exp Immunol. 80 (3): 314-23. -
Forte M et al. (1992) T-lymphocyte responses to Pneumocystis carinii in healthy and HIV-positive individuals.
J Acquir Immune Defic Syndr. 5 (4): 409-16. -
Hassell AB et al. (1992) MHC restriction of synovial fluid lymphocyte responses to the triggering organism in reactive arthritis. Absence of a class I-restricted response.
Clin Exp Immunol. 88 (3): 442-7. -
Pithie AD et al. (1992) Generation of cytolytic T cells in individuals infected by Mycobacterium tuberculosis and vaccinated with BCG.
Thorax. 47 (9): 695-701. -
Shokri, F. et al. (1993) Immunophenotypic and idiotypic characterisation of the leukaemic B-cells from patients with prolymphocytic leukaemia: evidence for a selective expression of immunoglobulin variable region (IGV) gene products.
Leuk Res. 17 (8): 669-76. -
Knox, P.G. & Young, L.S. (1995) Epstein-Barr virus infection of CR2-transfected epithelial cells reveals the presence of MHC class II on the virion.
Virology. 213 (1): 147-57. -
Uyama, H. et al. (2022) Competency of iPSC-derived retinas in MHC-mismatched transplantation in non-human primates.
Stem Cell Reports. 17 (11): 2392-408.
View The Latest Product References
- RRID
- AB_906085
MCA2497
0513R
150608
164090
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