HLA DP DQ DR antibody | Bu26
|Mouse anti Human HLA DP DQ DR antibody, clone Bu26 reacts with DP, DQ and DR beta chains, which are expressed by antigen presenting cells, B cells, monocytes and activated T lymphocytes.
The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In humans, this complex is referred to as the human leukocyte antigen (HLA) region. There are 3 major MHC class II proteins encoded by the HLA which are HLA DP, HLA DQ and HLA DR.
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.09% Sodium Azide (NaN3)
- Carrier Free
- Approx. Protein Concentrations
- IgG concentration 1.0mg/ml
- For research purposes only
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
|Application Name||Verified||Min Dilution||Max Dilution|
- Flow Cytometry
- Use 10ul of the suggested working dilution to label 1x106 cells in 100ul.
References for HLA DP DQ DR antibody
Chapple, M.R. et al. (1990) A phenotypic study of B lymphocyte subpopulations in human bone marrow.
Clin Exp Immunol. 81 (1): 166-72.
Forte M et al. (1992) T-lymphocyte responses to Pneumocystis carinii in healthy and HIV-positive individuals.
J Acquir Immune Defic Syndr. 5 (4): 409-16.
Knox, P.G. & Young, L.S. (1995) Epstein-Barr virus infection of CR2-transfected epithelial cells reveals the presence of MHC class II on the virion.
Virology. 213 (1): 147-57.
Hassell AB et al. (1992) MHC restriction of synovial fluid lymphocyte responses to the triggering organism in reactive arthritis. Absence of a class I-restricted response.
Clin Exp Immunol. 88 (3): 442-7.
Kumararatne, D.S. et al. (1990) Specific lysis of mycobacterial antigen-bearing macrophages by class II MHC-restricted polyclonal T cell lines in healthy donors or patients with tuberculosis.
Clin Exp Immunol. 80 (3): 314-23.
Shokri, F. et al. (1993) Immunophenotypic and idiotypic characterisation of the leukaemic B-cells from patients with prolymphocytic leukaemia: evidence for a selective expression of immunoglobulin variable region (IGV) gene products.
Leuk Res. 17 (8): 669-76.
Pithie AD et al. (1992) Generation of cytolytic T cells in individuals infected by Mycobacterium tuberculosis and vaccinated with BCG.
Thorax. 47 (9): 695-701.
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