Mouse anti Human High Mobility Group Protein B2 antibody, clone 3E5 recognizes human high mobility group protein B2, also known as HMGPB2 or HMG-2. Human high mobility group protein B2 is a 208 amino acid ~22 kDa multifunctional protein with roles in chromatin remodeling and posesses antimicrobial properties.
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein A
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- None present
- Recombinant protein corresponding to aa 1-196 of human Human High Mobility Group Protein B2.
- Approx. Protein Concentrations
- Ig concentration 0.5 mg/ml
- Fusion Partners
- Spleen cells from BALB/c mice were fused with cells from the Sp2/0 myeloma cell line.
- Store at -20oC only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
positive regulation of endothelial cell proliferation
damaged DNA binding
double-stranded DNA binding
single-stranded DNA binding
sequence-specific DNA binding transcription factor activity
DNA topological change
base-excision repair, DNA ligation
DNA fragmentation involved in apoptotic nuclear change
DNA bending activity
transcription activator activity
general transcriptional repressor activity
positive regulation of nuclease activity
positive regulation of DNA binding
positive regulation of erythrocyte differentiation
positive regulation of megakaryocyte differentiation
perinuclear region of cytoplasm
RAGE receptor binding
cellular response to lipopolysaccharide
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of High Mobility Group Protein B2 antibody
|Immunohistology - Paraffin
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
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Secondary Antibodies Available