Complement Factor H antibody | OX-24
Mouse anti Human Complement Factor H
- Product Type
- Monoclonal Antibody
- Complement Factor H
|Mouse anti Human Complement Factor H antibody, clone OX-24 recognizes the human serum complement protein factor H (155 kDa), binding to a different epitope from MRC OX23. The antibody also recognizes a 43-49 kDa truncated form of factor H present at low level (1-5 μg/ml) in plasma and urine. In an immunoprecipitation system, it recognizes factor H in other primates, but not in cow, sheep, pig, chicken or rabbit sera.
Mouse anti Human Complement Factor H antibody, clone OX-24 inhibits the binding of factor H to surface bound C3b, and recognizes Factor H in Western blotting procedures.
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.09% Sodium Azide
- Carrier Free
- Human complement factor H.
- Approx. Protein Concentrations
- IgG concentration 1.0mg/ml
- Fusion Partners
- NS-0 myeloma fused with spleen cells from BALB/c mice.
- For research purposes only
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
|Application Name||Verified||Min Dilution||Max Dilution|
References for Complement Factor H antibody
Alsenz, J. et al. (1985) Structural and functional analysis of the complement component factor H with the use of different enzymes and monoclonal antibodies to factor H.
Biochem J. 232 (3): 841-50.
Johnson, S.A. et al. (2010) Impact of compound heterozygous complement factor H mutations on development of atypical hemolytic uremic syndrome-A pedigree revisited.
Mol Immunol. 47 (7-8): 1585-91.
Kelly, U. et al. (2010) Heparan Sulfate, Including That in Bruch's Membrane, Inhibits the Complement Alternative Pathway: Implications for Age-Related Macular Degeneration.
J Immunol. 185: 5486-94.
Fontaine, M. et al. (1989) Truncated forms of human complement factor H.
Biochem J. 258 (3): 927-30.
Sim, E. et al. (1983) Monoclonal antibodies against the complement control protein factor H (beta 1 H).
Biosci Rep. 3 (12): 1119-31.
Hamidov, Z. et al. (2011) Reduced expression of desmocollin 2 is an independent prognostic biomarker for shorter patients survival in pancreatic ductal adenocarcinoma.
J Clin Pathol. 64 (11): 990-4.
Gurjar, B.S. et al. (2018) Characterization of genetic predisposition and autoantibody profile in atypical haemolytic-uraemic syndrome.
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"View all Anti-Human Products
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